Introduction Cerebral venous thrombosis (CVT) is still a significant diagnostic and therapeutic challenge, due to its high variability of clinical manifestations and its lack of a clear therapeutic consensus. Sources A search of the medical literature was made through PubMed using the conjoined terms ...
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Development The present paper reviews the fundamental aspects of the epidemiology, pathophysiology and aetiology of CVT. There is a comparison of the most common initial clinical manifestations along with a description of the most important neuroradiological studies needed to establish a diagnosis, all ...
Keywords:cerebral venous thrombosis,cerebral venous infarction,inflammation,pathophysiology,blood-brain barrier Data availability: ScienceOpen disciplines:Neurology Keywords:cerebral venous thrombosis,cerebral venous infarction,inflammation,pathophysiology,blood-brain barrier...
Purpose To provide new insights into the pathophysiology, prevention and diagnosis of cerebral venous thrombosis (CVT) associated with iatrogenic cerebrospinal fluid (CSF) leaks and/or external CSF drainage. Methods Case report and literature review. Results We describe the case of a 30-year-old wom...
Regarding pathophysiology, mechanisms can be attributed to ACE-2 receptors, platelet dysfunction, hypoxia and HIF, and the derangement of the complement system. However, whether COVID-19 is truly the causative factor participating through these mechanistic pathways or just a mere association remains ...
High suspicion is necessary, since the diagnosis of this potentially life‐threatening condition in COVID patients can be challenging. Evidence is still scarce on the pathophysiology and potential prevention of COVID associated CVT.doi:10.1111/ene.14727...
Pathophysiology There are two pathophysiologic mechanisms thought to contribute to the clinical manifestations of cerebral venous thrombosis. First, thrombosis of the cerebral veins leads to increased venous and capillary pressure, which leads to a decrease in cerebral perfusion. Decreased cerebral perfusion...
Thromboembolic complications in the nephrotic syndrome: pathophysiology and clinical management. Thromb Res. 2006; 118(3):397-407. This article on PubMed Monagle P, Chan A, Massicotte P et al. Antithrombotic therapy in children: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy...
antiphospholipid syndrome (APSmoderate-intensity oral anticoagulation (target INR 2-3Summary This chapter contains sections titled: The Antiphospholipid Syndrome Diagnosis of Antiphospholipid Syndrome Association of Antiphospholipid Antibodies and Thrombosis Pathophysiology of Antiphospholipid Syndrome Clinical ...