These changes are particularly prominent in the brain, where aging produces structural changes in the vessel wall, reductions in resting blood flow, and impairment of vasodilator responses. Impairment of the normal function of the blood鈥揵rain barrier also occurs with increasing age. Both oxidative ...
In Cerebral cortex: Neurodegenerative and age-related changes in structure and function of cerebral cortex (eds. A. Peters and J.H. Morrison), Vol. 14, pp. 21-47. Kluwer... MB Moss,RJ Killiany,JG Herndon - Springer US 被引量: 492发表: 1999年 Age-related changes in reactive oxygen ...
Studies have demonstrated that exercise benefits executive function. However, it remains unclear which type of exercise is optimal for preserving executive function among young adults and the cerebral blood flow (CBF) mechanisms that underlie exercise-in
Presenilins in the developing, adult, and aging cerebral cortex. Analysis of presenilin function in the adult cerebral cortex has revealed essential roles for presenilins in synaptic plasticity, long-term memory, and ... Wines-Samuelson,M. - 《Neuroscientist》 被引量: 116发表: 2005年 Stem Cells...
Whether this is a common phenomenon also existing in mild and moderate OSAS patients is an interesting question needing further experimental studies. Second, the function of CA decreases with aging but age is not a significant predictor for changes in cerebral hemodynamics in our models. One ...
of peripheral B cell pools that maintains maturity through self-renewal27. The most significant alterations of B cells during aging are loss of naïve B cells, impaired capacity to response to new antigens, reduction of clonal expansion of memory cells, and weakened antibodies function28. ...
Furthermore, the characteristic deposition of amyloid in vessels in AD may exacerbate the decline in vascular function and promote chronic hypoperfusion. Although not explicit from current studies, it is likely that the brain vasculature is continually modified by growth and repair mechanisms in ...
Associations between physical strength, cerebral function and mental health in independent-living elderly Japanese women Associations between Physical Strength, Cerebral Function and Mental Health in Independent-Living Elderly Japanese Women, "Environmental Health and Preventive Medic... K Hayashi,J Sato,N ...
An adequate oxygen supply is critical for proper brain function1, and deficiencies in tissue oxygen is a noted comorbidity in human diseases2 and aging3. For these reasons, there has been a great deal of interest in studying dynamics of cerebral oxygenation4,5,6,7,8. However, there is a ...
CP is a permanent condition that affects neuromuscular development. Consequently, treatment for this condition primarily seeks to maximize function and minimize symptoms such as spasticity, weakness, or contractures. In some cases, CP is associated with children who have developmental delay or mental re...