Adhesion moleculesBrain microvessel endothelial cellsVirusExpression of endothelial cell (EC) adhesion molecules is increased in inflammatory neurological disorders and this may regulate lymphocyte homing to the central nervous system (CNS). Viral encephalitis is characterised by lymphocytic infiltration of the...
Impaired neurite outgrowth of src-minus cerebellar neurons on the cell adhesion molecule L1. The nonreceptor tyrosine protein kinases pp60 c- src , p590 fyn , and pp62 c- yes are localized in growth cones of developing neurons, but their function ... MA Ignelzi,DR Miller,P Soriano,......
Intercellular adhesion molecule-1 (ICAM-1) is not involved in T cell adhesion to endothelial cells or cytotoxic endothelial cell lysis. Antibodies against human a 4 integrin (HP 2/1) and 1 (Al 1B2) inhibited T cell adhesion, but did not block cytotoxic endothelial cell lysis.doi:10.3109/...
Malcavernin/CCM2,orPDCD10/CCM3) [8,9]. Familial CCM lesions harbor biallelic endothelial cell (EC) mutations of the same CCM genes [10,11]. Sporadic
Amyloid β (Aβ) deposition is a hallmark of Alzheimer’s disease (AD). Vascular modifications, including altered brain endothelial cell function and structural viability of the blood-brain barrier due to vascular pulsatility, are implicated in AD pathol
Lastly, we analyzed the ligand-receptor pathways between M2 MΦ/MG and tip cells (Mki67+) with high or low expression of Bdbt10 (Fig. S4), finding that they primarily interact through Esam (cndothelial cell-selective adhesion molecule)-Esam, Col4a1-(Itga1+Itgb1) (collagen type IV alp...
The expression of endothelial leukocyte adhesion molecule-1 (ELAM-1), intercellular adhesion molecule-1 (ICAM-1), and vascular cell adhesion molecule-1 (VC... Endothelial cell adhesion molecule-1 (ELAM-1), intercellular adhesion molecule-1 (ICAM-1), and vascular cell adhesion molecule-1 (VCAM...
20 mg/kgDecrease the percentage of CD11b/CD18-positive neutrophils, down-regulate the expression of intercellular adhesion molecule-1(Li et al., 2012) Male SD rats induced by MCAO/R10 mg/kg, 20 mg/kgInhibit the expressions of MMP-9 and aquaporin 4(Li et al., 2013) ...
The identity of artery lysates was validated in the few randomly picked samples by Western blot immunostaining against the endothelial cell marker platelet endothelial cell adhesion molecule-1 (CD31), compared with lack of this staining in lysates of fetal cerebellum nervous tissue (supplemental Fig. ...
131 Impaired nitric oxide bioavailability may also contribute to endothelial dysfunction144 by increasing microvascular tone, endothelial cell adhesion molecule expression, cytokine production, and infected erythrocyte sequestration.145 These processes may cause varying degrees of functional obstruction and ...