Epilepsy surgery is an option for patients whose seizures remain resistant to treatment with anticonvulsant medications. The most common surgery is resection of the lesion that causes the epilepsy. Another common type of CM is arteriovenous malformation, which can cause seizures or hemorrhage. Three ...
Cerebral Cavernous Malformation (CCM) is a brain vascular disease with various neurological symptoms. In this study, we describe the inflammatory profile in CCM and show for the first time the formation of neutrophil extracellular traps (NETs) in rodents and humans with CCM. Through RNA-seq analys...
Cerebral cavernous malformations (CCMs) are low-flow vascular malformations in the brain associated with recurrent hemorrhage and seizures. The current treatment of CCMs relies solely on surgical intervention. Henceforth, alternative non-invasive therapies are urgently needed to help prevent subsequent hemorr...
Over the past half century molecular biology has led to great advances in our understanding of angio- and vasculogenesis and in the treatment of malformations resulting from these processes gone awry. Given their sporadic and familial distribution, their developmental and pathological link to capillary ...
Cerebral cavernous malformation (CCM) is a life-threatening disorder in which blood vessels in the brain are prone to hemorrhage. Kevin Whitehead et al. now show that CCM2, mutations in which are associated with CCM, is needed for specific aspects of end
The slow progression model of cerebral cavernous malformation (CCM) develops large lesions. A chronic model of CCM was generated by treatingCdh5(PAC)-Cre-ERT2/Ccm3f/f/R26R-Confettimice with low-dose tamoxifen.aScheme of treatment with tamoxifen at P2 and analysis at P8, P14 and P30.bRepres...
Thus, permanent cure of associated malformations might depend on the surgical treatment of the VM. We present a preliminary personal series and a thorough review of the literature. 展开 关键词: Keywords Cavernous hemangiomas Mixed malformations Surgical outcome Vascular malformations Venous malformations ...
Cerebral cavernous malformations (CCMs) are vascular abnormalities associated with deregulated angiogenesis. Their pathogenesis and optimal treatment remain unclear. This study aims to investigate the molecular signatures of cuproptosis, a newly identifi
Objective: We report a series of 13 patients with surgical treatment of cerebral cavernous malformation (CM). The aim of this study was to investigate postoperative patient disability and seizure control in patients with CM in order to clarify indications for neurosurgical removal. In our series we...
Advances in the treatment and outcome of brainstem cavernous malformation surgery: a single-center case series of 300 surgically treated patients. Neurosurgery. 2011;68(2):403–14; discussion 14-5. Article Google Scholar Baranoski JF, Bajaj A, Przybylowski CJ, Catapano JS, Frisoli FA, Lang ...