5. Ceramide-Dominant Skin Care Evolution for Skin Barrier Maintenance, Recovery and Repair The management of eczematous skin in both adults [91] and children (including neonates and infants) [92] is mainly aimed at reducing signs and symptoms (e.g., flaky, dry, irritated, and itchy skin) ...
The ceramides in the SC are unusual and very diverse, with a high percentage of very-long-chain N-acyl fatty acids. There are around 25 ceramide subclasses identified [48]. Most of these ceramides have a sphingoid base and an acyl chain linked by an amide bond. The acyl chain is ...