Williams A. Central nervous system regeneration - where are we? QJM, doi: 10.1093/qjmed/hct260 [Epub 13 January 2014].Williams A. (2014) Central nervous system regeneration-where are we? QJM Jan 13.Williams A. Central nervous system regeneration--Where are we? QJM 107: 335-339, 2014....
Central nervous system regeneration is driven by microglia necroptosis and repopulationFailed regeneration of CNS myelin contributes to clinical decline in neuroinflammatory and neurodegenerative diseases, for which there is an unmet therapeutic need. Here we reveal that efficient remyelination requires death ...
Regeneration in the Central Nervous System: Concepts and FactsRegeneration in the Central Nervous System: Concepts and FactsIn many years, based on Cajal's statement "… nerve paths are fixed, ended, immutable. Everything may die, nothing may be regenerated…" (Ramon y Cajal 1928) it has bee...
(1977) Regeneration in the central nervous system of a pulmonate mollusc, Melampus. Cell Tissue Res. 180, 529-536.Price, C. H. (1977). Regeneration in the central nervous system of a Pulmonate mollusc, Melampus. Cell Tissue Res. 180, 529-536....
Eventual Central Nervous System Regeneration?Eventual Central Nervous System Regeneration?ADVANCES in central nervous system (CNS) regeneration research may be reminding physicians to never say never. Any attempts at curing paralysis still are a long way off ( JAMA . 1981;245: 1201-1206,1293-1301)...
Since the end of World War II, there has been a renewed interest in the problem of regeneration of nervous tissue within the central nervous system. One of the reasons for this reevaluation of an old problem is the survival of so many paraplegics who, despite the trauma to their spinal ...
Central nervous system (CNS) presents a complex regeneration problem due to the inability of central neurons to regenerate correct axonal and dendritic connections. However, recent advances in developmental neurobiology, cell signaling, cell-matrix interaction, and biomaterials technologies have forced a re...
each of m and n is an integer of 1 to 6; and p is an integer of 1 to 3, or its salt has activity to protect neurons, activity to accelerate nerve regeneration and activity to accelerate neurite extension and hence is useful as a therapeutic agent for diseases in central and peripheral...
Microglia are resident macrophages of the central nervous system that have key functions in its development, homeostasis and response to damage and infection. Although microglia have been increasingly implicated in contributing to the pathology that underpins neurological dysfunction and disease, they also ...
point to the existence of a gut-to-brain axis that contributes to the spread of pathogenic Lewy bodies to the central nervous system. While neuronal dysfunction coupled with oxidative stress has a major role in the pathogenesis of PD, variations in numerous genes encoding key components of the ...