A couple of complex structures, one between PTU and sweet potato catechol oxidase (PDB ID: 1BUG) [14] and the other between tropolone and mushroom tyrosinase (PDB ID: 2Y9X) [15], have been published. Interestingly, these structures revealed that the inhibitors bind to the ...
Given the divergent interactions between other viruses and the DDR it will be intriguing to see how HBV copes with this multipronged host system. Keywords: hepatitis B virus; cccDNA; HBV minichromosome; DNA repair; DNA damage response; HBV cure 1. Introduction Hepatitis...