The complex interactions of cells with extracellular matrix (ECM) play crucial roles in mediating and regulating many processes, including cell adhesion, migration, and signaling during morphogenesis, tissue homeostasis, wound healing, and tumorigenesis. Many of these interactions involve transmembrane ...
Interactions between cells and the surrounding ECM are mediated by cellular adhesion molecules including selectins, immunoglobulins, cadherins, and integrins. Of particular relevance to renal fibrosis are integrins, which are heterodimeric glycoproteins composed of an 𝛼α and 𝛽β monomer [59,60,61...
actin cytoskeleton; BRAF RNAi; cell–cell adhesion; cell–ECM adhesion; endothelial monolayer; force application; magnetic beads 1. Introduction Cell adhesion molecules are involved in cell–cell interactions and cell–extracellular matrix (ECM) interactions. Among them, platelet endothelial cell adhesion...
fundamental cellular processes, such as the focal adhesion pathway, which allowed us to obtain detailed information on the active role that the down-regulation of ABCC6 could play in the biology of liver tumors, as it is involved not only in cell migration but also in cell adhesion and ...