How a bacterium becomes resistant to a particular metal depends on the number and location of cellular components sensitive to the specific metal ion. Other important selective factors include the nature of the uptake systems for the metal, the role and interactions of the metal in the normal ...
The rates at which these cellular functions responded to metal ion exposure were compared and related to the uptake rate of the ions into the cells. These rates of response were significantly different: DNA synthesis decreased the fastest, followed by protein synthesis, succinic dehydrogenase activity...
immune function, cell killing, and neuropeptide signaling (Supplementary Fig.2g). The only significantly enriched molecular functions related to metal ion binding (Supplementary Fig.
Moreover, EPS obviously plays a crucial role in H. salinarum metal ion resistance. Further efforts are required to elucidate the molecular basis and interplay of additional resistance mechanisms. 展开 关键词: SWATH-MS adhesion extracellular polymeric substances label-free quantification metal stress ...
et al. Outward- and inward-facing structures of a putative bacterial transition-metal transporter with homology to ferroportin. Nat. Commun. 6, 8545 (2015). Article CAS PubMed Google Scholar Pan, Y. et al. Structural basis of ion transport and inhibition in ferroportin. Nat. Commun. 11, ...
patterns in order to maintain growth under new conditions. Bacterial as well aseukaryotic cellssuch as yeast possess various response mechanisms to counterbalance fluctuations in growth parameters such as temperature, pH, solute concentration,oxygenation,metal ionconcentration, or high levels of organic ...
Typhimurium colonization, and our GO analysis results indicate the involvement of pyrB in the cellular amino acid metabolic process and involvement of pyrI in metal ion binding. In addition, polyamines are essential for biofilm formation in E. coli. PotFGHI functions as a compensatory importer of ...
There is a large and varied body of research literature on the ability of fields to effect changes in cellular models. Overall, the evidence for stimulation of cell division by ELF fields is at best equivocal. There is also no clear evidence that ELF magnetic fields can alter calcium ion hom...
Each molecule of MT can incorporate up to 7 zinc ions or other divalent metals. In addition to its metal storage function, MTs can also work as zinc acceptors and donors to exchange the metal ion with other proteins in the cells via its reversible dissociation of zinc ions and oxido...
For metal ion complementation assays, ZnSO4·7H2O (Fluka 96500), CuSO4 (VWR VW 3312–2), Fe(NO3)3·9H2O (Sigma F–1143) and MnCl2·4H2O (Sigma M8530) were dissolved in H2O to 100 mM. Lactic acid (Fluka 69775) was adjusted to pH 7 with NaOH and diluted with H2O to 0.5 ...