T cell metabolism is dynamic and highly regulated. While the intrinsic metabolic programs of T cell subsets are integral to their distinct differentiation and functional patterns, the ability of cells to acquire nutrients and cope with hostile microenvir
Genes up- and downregulated by S-293T cells are shown in a pie chart (FDR < 0.01, FC > 1.5). H SARS-CoV-2-S CAR-T cells incubated with S-293T cells were treated with or without felodipine, fasudil, imatinib, or caspofungin (10 μM) for two days, and cells in ...
substantially increased levels of a peroxisomal protein, PMP70, were found in the B cells activated by T-independent immunization, and chemical inhibition of respiration with thioridazine pointed to FAO by this organelle. Taken together with evidence of increased staining with fluorophore-labeled palmitat...
This could be explained by the lack of conversion of nitrates to ammonia by enteric bacteria, which normally occurs in vivo. Indeed, several enteric bacteria have shown the ability of catalytic reduction of nitrates to ammonia via nitrites during dissimilatory respiration [51], and chronic exposure...