Das A, Sinha M, Datta S, Abas M, Chaffee S, Sen CK, Roy S (2015) Monocyte and macrophage plasticity in tissue repair and regeneration. Am J Pathol 185:2596–2606. doi:10.1016/j.ajpath.2015.06.001 Article CAS PubMed Google Scholar Arnold L, Henry A, Poron F, Baba-Amer Y, van...
Cellular and Molecular Basis of Regeneration: From Invertebrates to Humansdoi:10.1111/j.1067-1927.2004.012317.xFerretti, PatriziaGeraudie, JacquelineJohn Wiley & Sons, LtdWound Repair and RegenerationHall BK. The bone. In: Cellular and molecular basis of regeneration. Ferretti P, Geraudie J, ed(...
Sphingolipid metabolism controls mammalian heart regeneration. Cell Metab. 36, 839–856.e8 (2024). Article CAS PubMed Google Scholar Alvarez, S. E. et al. Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2. Nature 465, 1084–1088 (2010). Article CAS PubMed ...
Here, we focus on the recent lessons from lower organism CNS regeneration genetics and how such findings are starting to illuminate our understanding of NSC signaling pathways in humans. These findings will allow us to improve upon our knowledge of endogenous NSC function, the utility of exogenous...
However, these cells are highly susceptible to damage from an array of factors, resulting in degeneration and ultimately irreversible hearing loss in humans. Since the discovery of hair cell regeneration in birds, there have been tremendous efforts to identify therapies that could promote hair cell ...
recently, the team found that, even in young mice, the Yamanaka factors canaccelerate muscle regeneration. Following these initial observations, other scientists have used the same approach to improve the function of other tissues like the heart, brain and optic nerve, which is involved in vision...
(arrowhead) in the MZ or along the radial fibers traversing to the radial glia cells in the VZ at E15.5 in mice (a,n = 6 independent experiments) and GW11 in humans (b,n = 3 independent experiments). Dashed lines indicate the surface of the third ventricle. Dotted lines ...
The frequency of enterocytes, which express IL22RA1, was correlated with the expression by CD4+ activated Foshi T cells of IL22, which regulates intestinal regeneration (Pelczar et al., 2016; Figure 6E; Spearman’s ρ = 0.55). We validated this interaction in human colon spheroid culture, ...
which promotes CRC cell proliferation and progression172. However, not all SNORDs do not participate in methylation. In HCC, lncRNA associated with liver regeneration (LALR1) andSNORD72are highly upregulated, andLALR1binds toSNORD72, which promotes the stability of inhibitor of DNA binding 2 mRN...
The brains of humans and other mammals are highly vulnerable to interruptions in blood flow and decreases in oxygen levels. Here we describe the restoration and maintenance of microcirculation and molecular and cellular functions of the intact pig brain under ex vivo normothermic conditions up to fo...