Rho GTPase is a regulator controlling the cytoskeleton in multiple contexts such as cell migration, adhesion, and cytokinesis. Upon binding to GTP, Rho exerts its functions through downstream Rho effectors such as ROCK/Rho-kinase/ROK, mDia, Citron , PKN, Rhophilin, and Rhotekin. Our knowledge...
Other cells acquire specialized functions as they mature. These cells cooperate with other specialized cells and become the building blocks of large multicellular organisms, such as humans and other animals. Although cells are much larger than atoms, they are still very small. The smallest known ...
(2007). Metabolism, cytoskeleton and cellular signalling in the grip of protein Nepsilon - and O-acetylation. EMBO Rep 8, 556-62.Yang, X.J., and Gregoire, S. (2007) Metabolism, cytoskeleton and cellular signalling in the grip of protein Nε- and O-acetylation. EMBO Rep 8: 556-562....
Individual cells contact and interact with other cells and with the extracellular matrix--a network of secreted proteins and carbohydrates that fills the intercellular spaces. The extracellular matrix helps cells to bind together and regulates a number of cellular functions, such as adhesion, migration...
Among the physicochemical cues in the cellular microenvironment that orchestrate cell processes, the different levels of curvature in the extracellular matrix and intrinsic to the tissues play a pivotal role in the spatiotemporal control of key cellular functions. Curvature influences multicellular organizati...
Identification of the binding interface involved in linkage of cytoskeletal protein 4.1 to the erythrocyte anion exchanger. Linkages of the cytoskeleton to integral membrane proteins of the plasma membrane have been shown to be important for diverse cellular functions. The eryth... T Jöns,D Drenck...
Functions of microtubules in the Saccharomyces cerevisiae cell cycle. We used the inhibitor nocodazole in conjunction with immunofluorescence and electron microscopy to investigate microtubule function in the yeast cell cycle... Jacobs,W C. - 《Journal of Cell Biology》 被引量: 779发表: 1988年 Sst...
Cells can come in many shapes and sizes, which they maintain through their cytoskeleton. This structure has been the subject of fundamental interest in the field of cell mechanics for it greatly defines the physical properties and behaviors of a cell. However, the cell membrane, nucleus, and ...
11 . The interplay between adhesion, the cytoskeleton and morphology in substrate-attached cells. Exp Cell Res - Smith, Rees - 1977 () Citation Context ...from these in vitro studies. One of the primary stress fiber functions is a role in cell adhesion to the substrate. The relationship ...
Super-resolution imaging of the neuronal cytoskeleton Ciarán Butler-Hallissey Christophe Leterrier ReviewsOpen Access04 Dec 2024 npj Imaging Volume: 2, P: 50 Robust self-supervised denoising of voltage imaging data using CellMincer Brice Wang Tianle Ma Mehrtash Babadi ResearchOpen Access04 Dec...