Sunitinib-induced maladaptive autophagy selectively degrades the cardiomyocyte survival mediator CCN2 (cellular communication network factor 2) through the TOLLIP (toll interacting protein)-mediated endosome-related pathway and cardiomyocyte-specific knockdown of Ccn2 through adeno-associated virus serotype 9 ...
To investigate the effects of cellular communication network factor 1 (CCN1), a critical matricellular protein, on alveolar bone regeneration, and to elucidate the underlying molecular mechanism.In the process of orthodontic tooth movement, bone deposition on the tension side of human periodontal ligame...
Therefore, it is reasonable to explore the mutual communication and interaction between HSCs and BECs during liver regeneration. It has been demonstrated that BECs can attract lobular HSCs into portal tracts, and PDGF-BB is a key factor regulating this chemotaxis. Bile duct segments isolated from ...
After cessation of blood flow or similar ischaemic exposures, deleterious molecular cascades commence in mammalian cells, eventually leading to their death1,2. Yet with targeted interventions, these processes can be mitigated or reversed, even minutes or hours post mortem, as also reported in the is...
Cell communication is needed for organ function and stress responses, especially in the heart. Cardiac fibroblasts, cardiomyocytes, immune cells and endothelial cells comprise the major cell types in the ventricular myocardium that together coordinate all functional processes. Critical to this cellular net...
1. A method of operating a pool of mobile switching apparatuses provided for a mobile cellular communication network, comprising the steps of: a) issuing a paging message to an access network through a first mobile switching apparatus (12-2) in the pool of mobile switching apparatuses; b) rec...
binding factor 1 and 2); ELOVL (protein coding fatty acid elongase 2 gene); LC3 and LC1 (microtubule-associated protein light chain 3); ETC (electron transport chain); ATP (adenosine triphosphate); BAX (BCL2 associated X-apoptosis regulator); and Bcl-2 (BCL2-apoptosis regulator Bcl-2). ...
无线通信原理与应用英lecture2(英文)Chapter2:TheCellularConcept-SystemDesignFundamentals Lecture2 2020/7/18 1 2.1TheConcept:CellularNetworks 2020/7/18 2 geometricshapes Circle:Acr23.14r2 Equilateraltriangle:At1.3r2 Square:Hexagon:As2.0r2 Ah2.6r2 2020/7/18 3 Cellularcoveragerepresentation 2020/7/...
To delineate the molecular associations underlying inter-cellular relationships, we first constructed a cellular communication network using potential receptor-ligand pair interactions. In the tLung, we substantiated the dominant crosstalk between the tS2, a novel cancer cell state associated with LUAD pr...
whileCLDN2+AT2 cells possessed the largest number of interactions as the signal receivers (Fig.4a). Considering the cell communication network topology, fibroblast and myeloid cells respectively had the largest outcoming and incoming degrees, and theCLDN2+AT2 cells displayed the third highest incoming...