Cells Tissues Organs aims at bridging the gap between cell biology and developmental biology and the emerging fields of regenerative medicine (stem cell biology, tissue engineering, artificial organs, in vitro systems, and transplantation biology). Cells Tissues Organs offers a rapid and fair peer rev...
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cells of the same origin gradually differentiate into different levels, giving rise to cell populations with different morphological structures and functional characteristics, thus constructing the tissues and organs necessary for multicellular life [1,2]. The phenomenon of cells deviating from normal termi...
Tissue-resident memory CD8+ T cells (TRM cells) are crucial in protecting against reinvading pathogens, but the impact of reinfection on their tissue confinement and contribution to recall responses is unclear. We developed a unique lineage tracer mouse
Like naive T cells, Tcm cells recirculate between blood, the T cell zones of secondary lymphoid organs, and lymph. Tem cells recirculate between nonlymphoid tissues, lymph, lymph nodes (where they might pass through via the sinuses, without entering the T cell zone), and blood. Trm cells ...
Regenerative medicine is a recent and emerging branch of medical science, addressing functional restoration of specific tissues and/or organs of patients suffering from severe injuries or chronic diseases in a condition where the organism’s own regenerative responses do not suffice [1]. Stem cells ...
cells of the ILC3 group that mainly reside in lymphoid tissues; they are involved in generating secondary lymphoid organs during embryogenesis. MHCII a protein complex expressed by professional antigen-presenting cells that presents peptides to CD4+ T cells to initiate an immune response. Natural cy...
strategies per patient basis. Developing patient-specific in silico models of different organs with tumor types at distinct states of malignancy will require advanced imaging methods (such as standard and high definition Fourier Transform Infrared (FTIR) imaging) being capable of acquiring stromal ...
γδ T cells are a unique T cell subpopulation that are rare in secondary lymphoid organs but enriched in many peripheral tissues, such as the skin, intestines and lungs. By rapidly producing large amounts of cytokines, γδ T cells make key contributions to immune responses in these tissues...
alternative SCs and host complementation strategies should be developed to regenerate various tissues and cells for clinical application. The integumentary chimera, for instance, has been established to generate intact skin tissue and its appendage organs [24,261]. This chimera transplants interspecies or...