Neural crest cells are highly multipotent stem cells, but it remains unclear how their fate restriction to specific fates occurs. The direct fate restriction model hypothesises that migrating cells maintain full multipotency, whilst progressive fate restriction envisages fully multipotent cells transitioning...
[10], the substantial ion release from both intact and competent cells indicates that weakening of the cellular membrane is significantly elevated at high temperatures. Cytoplasmic membranes of other intact cells have been reported to be weakened by experiencing domain melting and rigidity reduction ...