In adult skeletal muscle, a particular cell type named satellite cells are believed to form a stable, self-renewing pool of stem cells. However, this tissue contains also at least two other types of muscle-derived stem cells: i) a cell population so-called MDSC, which may represent a ...
Skeletal muscle stem cells (MuSCs, also called satellite cells) are the source of the robust regenerative capability of this tissue. The hallmark property ... H Margaret,L Hsiao-Fan,GEL Jones,... - 《Journal of Cell Science》 被引量: 0发表: 2023年 Stem Cells of the Reproductive System:...
Adult stem cells are indispensable for tissue regeneration, but their function declines with age. The niche environment in which the stem cells reside plays a critical role in their function. However, quantification of the niche effect on stem cell function is lacking. Using muscle stem cells (Mu...
A New Look at the Origin, Function, and “Stem-Cell” Status of Muscle Satellite Cells Taken together, these studies provide the first evidence that pluripotential stem cells are present within adult skeletal muscle. Tissue-specific stem cells, ... Patrick Seale,Michael A. Rudnicki - 《Developm...
Connective tissue - Migrating Cells, Fibers, Matrix: In addition to the relatively fixed cell types described above, there are free cells that reside in the interstices of loose connective tissue. These vary in their abundance and are free to migrate thr
Adult muscle contains a population of resident stem cells, called satellite cells, and an important unresolved question is whether satellite cells play a role in muscle homeostasis and sarcopenia4–7. Genetic labelling and ablation studies have definitively established that satellite cells are the ...
Recent studies have shown that umbilical cord mesenchymal stem cells have an anti-aging effect in ovaries, but the cellular and molecular mechanisms of HA-MSC ovarian anti-aging remain to be studied. Therefore, we conducted a 10X Genomics single-nucleus
tissue regeneration, and tumor suppression but also in the pathogenesis of age-related degenerative diseases, malignancies, metabolic diseases, and kidney diseases. The senescence of renal tubular epithelial cells (RTEC) constitutes a critical cellular event in the progression of acute kidney injury (AKI...
During embryonic development, epithelial cell blocks called somites are periodically formed according to the segmentation clock, becoming the foundation for the segmental pattern of the vertebral column. The process of somitogenesis has recently been recapitulated with murine and human pluripotent stem cell...
Muscle(from Latinmusculus, diminutive ofmus"mouse") is the contractile tissue of the body and is derived from the mesodermal layer of embryonic germ cells. Muscle cells contain contractile filaments that move past each other and change the size of the cell. They are classified as skeletal, card...