Siegel G. Connective tissue: more than just a matrix for cells. In: Greger R, Windhorst U, editors. Comprehensive human physiology, vol. 1. Berlin, Heidelberg: Springer-Verlag; 1996. p. 173-224.G. Siegel, Connective tissue: more than just a matrix for cells, in: R. Greger, U. ...
- when cells adhere to soft pliable substrate, they generate less organized actin and smaller, weaker focaladhesions 5. Extracellular matrix (ECM) - Mechanical support (provide stability and elasticity of tissue) - Selective barrier between tissue types (e.g. impermeable to cells) - Cell guidance...
Connective tissue that underlies the epithelium of the mucosa and contains stromal and haematopoietic cells. Peyer's patches Groups of lymphoid aggregates located in the submucosa of the small intestine that contain many immune cells, including B cells, T cells and dendritic cells. They have a lum...
Aging of the intercellular matrix in relation to the fibroblast Connective tissue forming cells–a retrospective viewdoi:10.1080/00365517409102148R.UniversityRossUniversityInformaworldScandinavian Journal of Clinical & Laboratory Investigation
Chimeric antigen receptor (CAR) T cell therapy, which targets tumors with high specificity through the recognition of particular antigens, has emerged as one of the most rapidly advancing modalities in immunotherapy, demonstrating substantial success aga
Evolutionary structure of CARs. (A) Primary structure of CARs. (B) Evolution of the general structure across five generations of CARs. First generation CARs contain only an antigen-recognition domain and a CD3ζ T cell signaling domain. Second generation CARs contain an additional costimulatory doma...
Both benign and malignant neoplasms are composed of (i) neoplastic cells that form the parenchyma, and (ii) the host-derived non-neoplastic stroma that is composed of connective tissue, blood vessels, and other cells, and supports the tumor parenchyma. The tumor stroma serves a critical function...
Connective tissue - Migrating Cells, Fibers, Matrix: In addition to the relatively fixed cell types described above, there are free cells that reside in the interstices of loose connective tissue. These vary in their abundance and are free to migrate thr
(d,e) DES (mesoderm), (g,h) FoxA2 (endoderm), (c,f,i) as the corresponding negative control; (E) HE staining results (100×, 20 μm), (a) proved to be the mitotic phase of the tumor, (b) nerve cells (ectoderm), (c) connective tissue (mesoderm), (d) glands (endoderm);...
After digestion, the OLABs were released from their matrix using a 40 μm cell strainer (352340, Thermo Fisher). Then, 5 × 104 cells were transferred to a 75 cm2 flask. The epithelium of the attached gingiva was separated from the underlying connective tissue by digestion with 2.5 mg of...