apoptosis, cell cycle, mitosis, Fas/CD95, etoposideApoptosis is induced by various stresses generated from the extracellular and intracellular environments. The fidelity of the cell cycle is monitored by surveillance mechanisms that arrest its further progression if any crucial process has not been ...
When CDK1 is phosphorylated into CDK1 (p-cdc2-Tyr15-Thr14) by Weel and Mytl protein kinase, CDC25C dephosphorylate it into active CDK1 (p-cdc2-Tyr15), which combines Cyclin B1 and phosphorylate the substrate Survivin into Survivin (p-Thr14), thus promoting the cells into mitosis phase...
The proteolysis of mitotic cyclins in mammalian cells persists from the end of mitosis until the onset of S phase EMBO J., 15 (1996), pp. 5280-5289 CrossrefView in ScopusGoogle Scholar 9 T. Buchou, O. Kranenburg, H. van Dam, D. Roelen, A. Zantema, F.L. Hall, A. van der Eb...
αB-Crystallin Interacts with Cytoplasmic Intermediate Filament Bundles during Mitosis The small heat-shock protein αB-crystallin interacts with intermediate filament proteins. Using cosedimentation assay, we showed previously that in vitro ... NM Portier - 《Experimental Cell Research》 被引量: 74发表...
In the Yoshida sarcoma a strain of tumor cells is present which have their own characteristic chromosome constitution and multiply by regular mitosis. The ... S Makino - 《Chromosoma》 被引量: 66发表: 1950年 Fine Structure of Chromosomes in the Mitotic Prophase of Ascites Tumour Cells Ascites ...
The G2-checkpoint is implemented by suppressing the activity of Cdc25C, a phosphatase that activates CDK1 and drives cells into mitosis. ATM and ATR convey inhibitory signals to CDC25C through CHK2 and CHK1, respectively4. The dominant role noted above for ATR in the checkpoint response sugg...
Large-scale chromatin organisation in interphase, mitosis and meiosis. Biochem J. 2019;476:2141–56. Article CAS PubMed Google Scholar Collas P, Liyakat Ali TM, Brunet A, Germier T. Finding friends in the crowd: three-dimensional cliques of topological genomic domains. Front Genet. 2019;10...
Studies the differential taxol-dependent arrest of transformed and nontransformed cells in G1 phase of the cell cycle. Cell mortality; Cell blockage in mitosis; Characterization of G1 arrest; Existence of microtubule sensitive step in G1 regulation of nontransformed fibroblast cells; Distinct role of...
The assembly of a bipolar microtubule-based spindle is crucial for the accurate and timely segregation of the chromosomes into the two daughter cells during mitosis. Three microtubule nucleation pathways function in mitotic cells to contribute microtubules to the assembling spindle, namely the centrosome...
(h) MDA-MB-231 cells were either synchronized in G1/S phase or in mitosis. Cells were then released into the cell cycle and collected at the indicated time points. The co-immunoprecipitated GCN5/SIRT1 levels were normalized with immunoprecipitated WEE1 levels expressed as the normalized ratio...