Prostate cancer (PCa) is today the second most common cancer in the world, with almost 400,000 deaths annually. Multiple factors are involved in the etiology of PCa, such as older age, genetic mutations, ethnicity, diet, or inflammation. Modern treatment of PCa involves radical surgical treatme...
The most prevalent chromatin-based scATAC-seq clusters in terms of cell number (0, 1, and 2) were persistent (Fig.1e) and defined by fewer than 20 unique DARs, suggesting that 74% of the cells share an overall similar chromatin-accessibility profile during the development of ENZ resistance....
PSCs form colonies as they grow, and spontaneous differentiation inevitably occurs along the rim of these colonies in areas that lack cell-to-cell contact; because of this, undifferentiated cell populations would diminish if differentiated cells are not removed properly. Seeding cells on a less ...
In this review, recent advancements in the incorporation of 2D materials into PSCs are summarized. To gain a deeper understanding of 2D materials and the interfaces they form, we first present a brief introduction to the fundamental properties of 2D materials and vdW heterostructures based on them...
In recent years, stem cell therapy has become a very promising and advanced scientific research topic. The development of treatment methods has evoked great expectations. This paper is a review focused on the discovery of different stem cells and the pot
Distinct polarized outer and apolar inner cell populations form during the morula phase of development. In the subsequent blastocyst stage, the outer cells give rise to the trophoblast lineage and later form most cells in the placenta. The inner cells give rise to the inner cell mass, which ...
This leads the cell to be more rigid and extend about its periphery. Most cell types, including endothelial cells, myocytes and fibroblasts spread further, adhere better, and appear to survive better on stiffer matrices, and some cannot grow on soft surfaces. The substrates' elastic modulus ...
also be used to stimulate endogenous cellsin situto grow and differentiate into specific cell types. The most important subcategory of adult stem cells is MSCs.In particular, these are the most widely used adult stem cells at present. Although MSCs were isolated initially from bone marrow, other...
The cellular landscape of the human intestinal tract is dynamic throughout life, developing in utero and changing in response to functional requirements and environmental exposures. Here, to comprehensively map cell lineages, we use single-cell RNA seque
Cells were allowed to grow and form sprouts for 7–11 days. As a control of the differentiation system, human dermal microvascular endothelial cells (HDMEC; PromoCell, Heidelberg, Germany) were used in the same experimental conditions. However, sprouts were already formed by 24 h in vitro with...