A high-performance register file is implemented in a multi- block structure consisting of sub-arrays and associated multiplexing circuits. For a given port, the outputs of all multiplexer circuits are dotted together to form a single global output. The multiplexer circuits may be completely external...
In the sample where an equal number of 293T and Jurkat cells was mixed, PC 1 separated cells into two clusters of equal size (Fig. 2e, Supplementary Fig. 4a and Supplementary Data 1). Based on the expression of cell type-specific markers, we infer that one cluster corresponds to Jurkat...
Abstract. A central problem of geometry is the tiling of space with simple structures. The classical solutions, such as triangles, squares, and hexagons in
Tuft cells are rare, chemosensory epithelial cells that were identified over 60 years ago24,25. These rare cells did not generate interest until three reports in 2016 identified tuft cells to be central in type 2 immune circuits and crypt epithelial cell progenitors26,27,28. A recent study by...
In the specific field of application of the present invention there are provided integrated memory circuits including, in addition to a plurality of memory cells arranged in one or more matrixes, external or peripheral circuits in which components are structurally similar to the cells and are provide...
Stem cells are a unique class of cells that can be distinguished by their distinct capabilities to differentiate into specialized lineages for the self-repair of various tissues and organs in the human body [6]. As such, controlling stem cell fate has become one of the most important topics ...
Review of experimental and modelling developments for ceria-based solid oxide fuel cells free from internal short circuits J Mater Sci, 55 (2020), pp. 1-23, 10.1007/s10853-019-03876-z Google Scholar 135 H. Chen, H. Zhu, S. Shen, et al. Numerical study on charge transport and electroch...
In metazoan a possible strong evolutionary pressure for the wiring of these RBP-mediated post-transcriptional looping circuits could derive from the need to regulate protein synthesis of maternal mRNAs in oocytes and in early embryo development, a well-studied process in C. elegans and Drosophila[42...
J. Synaptic activity and the construction of cortical circuits. Science 274, 1133–1138 (1996). Article CAS PubMed Google Scholar Ackman, J. B., Burbridge, T. J. & Crair, M. C. Retinal waves coordinate patterned activity throughout the developing visual system. Nature 490, 219–225 (...
This issue is further exacerbated by the additional complexity of multi-color systems, which use multiple expression constructs, each one needing separate optimization, limiting the broad use of CRISPR for genome imaging applications. Here we report a simple and versatile CRISPR imaging system based ...