the burping macrophage, interactive animations (Cell Model, Mitosis, HowBig?), matching games, and jigsaw puzzles. Instructions for installation on your computer are in the 78mb ZIP download. Install it on classroom computers or share copies of the ZIP file with others. The online CELLSalive!w...
proliferative response [38] (Fig.2A). Once YAP translocates to the nucleus, it drives the expression of a variety of target genes involved in the control of S-phase entry and mitosis. Thus, YAP might fulfill the function of a regulator of cell proliferation and organ size. To confirm these...
Polyploidy occurs in some Bacteria [150] and Archaea [151], as well as chloroplasts [152]. Its potential roles in the evolution of the early nucleus and mitosis have been investigated by computer simulation [153]. Briefly, polyploidy, by itself, provides a short-term advantage over monoploid...
The transforming factor GF-β (TGF-β1) performs several essential functions: it stimulates mitosis in fibroblasts, inhibits the proliferation of epithelial cells, and induces apoptosis. Increased expression of TGF-β1 on stromal cells is associated with an increase in the stromal compartment [81]....
It cannot be excluded that, when senescent cells are in the cell cycle, they may replicate their DNA but skip or slip mitosis, resulting in polyploidy, and then return to the proliferative state through depolyploidization. Thus, we have postulated that senescent cancer cells do not exit the ...
Tip60 is also known to be involved in protein modifications for several critical targets, such as acetylation and crotonylation, to execute accurate mitosis in several cancer cells [51,52,53,54,55,56]. In this study, mitotic cells were accumulated in the SVZ and most likely in the VZ of ...
horrens extract induced cell proliferation, increased S and G2 phases, and finally mitosis [37]. Moreover, the effects of aqueous extract of H. parva on proliferation-related peptides in hUC-MSCs were assessed. Aqueous extract of H. parva or EGF upregulated expression of cyclin D1, cyclin ...
Cellulose micro/nanomaterials (CMNM), comprising cellulose microfibrils (CMF), nanofibrils (CNF), and nanocrystals (CNC), are being recognized as promising bio-nanomaterials due to their natural and renewable source, attractive properties, and potential