the burping macrophage, interactive animations (Cell Model, Mitosis, HowBig?), matching games, and jigsaw puzzles. Instructions for installation on your computer are in the 78mb ZIP download. Install it on classroom computers or share copies of the ZIP file with others. The online CELLSalive!w...
Why does a cell undergo mitosis? Why do epithelial cells have many mitochondria? Why is the pentose phosphate pathway active in dividing cells? Why do some enzymes use GTP instead of ATP? Why do cells go through cell differentiation? Why are enzymes important to cells? Why is the cell cycle...
proliferative response [38] (Fig.2A). Once YAP translocates to the nucleus, it drives the expression of a variety of target genes involved in the control of S-phase entry and mitosis. Thus, YAP might fulfill the function of a regulator of cell proliferation and organ size. To confirm these...
Stem cells are a kind of cell that has the capacity to self-renew to produce additional stem cells by mitosis, and also to differentiate into other— more mature—cell types. Stem cells are usually categorized as multipotent (able to give rise to multiple cells within a lineage), pluripotent...
During mitosis, mammalian cells disassemble and reassemble the ribbon in a finely tuned process14; such a level of regulation suggests that the ribbon architecture must be functionally important. This conclusion is supported by the existence of several pathologies in which ribbon breakdown (Golgi “...
The apoptotic/abnormal mitosis index was estimated based on the following equation: (number of cells undergoing apoptosis or abnormal mitosis during treatment/total number of cells) × 100. 2.6.2. Apoptosis analysis by flow cytometry and cell counts To assess the apoptotic effect of Cur, DeMC, ...
It cannot be excluded that, when senescent cells are in the cell cycle, they may replicate their DNA but skip or slip mitosis, resulting in polyploidy, and then return to the proliferative state through depolyploidization. Thus, we have postulated that senescent cancer cells do not exit the ...
Ki67 staining patterns indicate different stages of the cell cycle: asterisks indicate cells in G1/S phases, arrows indicate cells in G2 phase, and triangles indicate cells in mitosis. The scale bar = 50 µm is the same in every image. The adjacent graphs show the changes induced after ...