Cisplatin Versus Carboplatin In Patients Over 70 Years With Advanced Head And Neck Squamous Cell Carcinoma With Curative Intent Concurrent Chemo? Radiation. Predictors Of Oncological Outcomessubramaniam, Narayanakumar, Narenderbalasubramaniam, Deepak
接下来，研究人员评估了 FAH 表达与 EOC 患者临床治疗结果的相关性。他们对来自 57 名卵巢癌患者肿瘤组织中衍生的原发性 EOC 细胞进行了定量，然后再用基因毒性化疗药物 顺铂（cisplatin）或 依托泊苷（etoposide）处理后监测了细胞凋亡情况。结果显示，在接受基因毒性药物治疗的 EOC 细胞中，FAH 表达与细胞凋亡率呈...
The cytotoxic activity of cis -[((1 R ,2 R )-1,2-cyclohexanediamine- N , N' )bis(myristato)]platinum (II) (SM-11355) was evaluated in a cisplatin (CDDP)-resistant tumor cell line, and compared with that of CDDP. H4-II-E/CDDP with acquired resistance to CDDP was established by...
Cisplatin-based adjuvant chemotherapy in patients with completely resected non-small-cell lung cancer. CONCLUSIONS: Cisplatin-based adjuvant chemotherapy improves survival among patients with completely resected non-small-cell lung cancer... None - 《N Engl J Med》 ...
2) 应用目的:用Ca2+荧光探针Rhod-2 AM(MX4507-50UG)检测顺铂(cisplatin)对HeLa细胞线粒体Ca2+水平的变化。 Fig 2. 顺铂增加细胞浆和线粒体内游离Ca2+水平。A)HeLa细胞用顺铂(2.5, 5 or 10 µg/ml)处理0h,6h,12h和24h后,用荧光钙离子探针Fluo-4 AM孵育。细胞浆Ca2+浓度用共聚焦显微镜观察(bar,40...
Taxol, 5-flourouracil, and cisplatin were used as the positive controls. 2.10.3. 2-[N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)amino]-2-deoxy-d-glucose (2-NBDG) Glucose Uptake Assay This experiment was consistent with those reported in our previous work [26]. The HepG2 hepatoma cells ...
Lopez JA, Mann J, Grapski RT, Nassif E, Vannicola P, Krikorian JG, Finkel H (1985) Etoposide and cisplatin salvage chemotherapy for small cell lung cancer. Cancer Treat Rep 69: 369–371Lopez J A, Mann J, Grapski R T: Etoposide and cisplatin salvage chemotherapy for small cell lung ...
Using lung cancer cell lines, ABC-1 and SBC-3, we examined the cytotoxic effect of the schedule, as well as the effect of cisplatin on topoisomerase I activity. Cytotoxicity was determined by MTT assay. ABC-1 or SBC-3 cells were incubated with or without various concentrations of both ...
Objective To evaluate the efficacy and toxicities of irinotecan(CPT-11) combined with cisplatin(DDP)(IP regimen) in the treatment of patients with advanced non-small cell lung cancer(NSCLC).Methods Thirty one patients with advanced NSCLC received the IP regimen chemotherapy: CPT-11 100 mg·m-2...
Cisplatininducescellcyclearrestandsenescencevia upregulatingP53andP21expressioninHepG2cells QUKai 1# ,LINTing 1,2# ,WEIJichao 1,3 ,MENGFandi 1 ,WANGZhixin 1 ,HUANGZichao 1 ,WANYong 1 ,SONG Sidong 1 ,LIUSinan 1 ,CHANGHulin 1 ,DONGYafeng 4 ,LIUChang 1,2 * 1 DepartmentofHepatobiliarySur...