Although cells can have different shapes and functions, the DNA sequence in all cells of one individual is in principle identical (with the exception of certain blood cells). Other prominent structures in the cell are the mitochondria. These organelles are present in large numbers and generate ...
Although this transport mode is associated with all organelles, it is especially relevant for organelles like mitochondria that are excluded from vesicular traffic. Non-vesicular lipid exchange occurs at sites of close contact (10–30 nm) between organelles, where lipid transport proteins (LTPs) ...
the cell cycle is defined as the period between successive divisions of a cell. During this period, the contents of the cell must be accurately replicated. Microscopists had known about cell division for more than one hundred years
BBA Molecular Cell Researchfocuses on understanding themechanismsofcellular processesat themolecularlevel. These include aspects of cellular signaling, signal transduction, cell cycle, apoptosis, intracellular trafficking, secretory and endocytic pathways, biogenesis of cell organelles, cytoskeletal structures, ce...
Oligodendrocyte processes display intense bidirectional movement of cytoplasmic organelles. Movement of surface components also occurs since GC molecules cross-linked by antibodies move from the processes towards the cell body. Thus, oligodendrocytes cultured without neurons develop on schedule a complex ...
The endomembrane system and cytoskeleton are coadapted and interact in numerous ways. Branching networks of actin attach to plasma membrane, endomembranes and organelles by specific protein links. The endomembrane system fundamentally depends on coat-mediated budding of vesicles from one compartment, unco...
Nucleoid (拟核) • The nucleoid (meaning nucleus-like) is an irregularly-shaped region within the cell of a prokaryote (原核生物)that contains all or most of the genetic material, called genophore (基因带). Organelles (细胞器) Specialized Work Units • All eukaryotic cells contain most ...
In addition, some down-regulated genes were associated with vesicular transport, especially the endosomal recycling pathway (Table 2). Rab proteins are monomeric small GTPases that regulate transport between organelles (48). The Rab family contains more than 60 members in humans. The list of down...
P. Probing and engineering liquid-phase organelles. Nat. Biotechnol. 37, 1435–1445 (2019). CAS PubMed Google Scholar Skamrahl, M., Colin-York, H., Barbieri, L. & Fritzsche, M. Simultaneous quantification of the interplay between molecular turnover and cell mechanics by AFM–FRAP. Small...
The formation and maintenance of subcellular structures and organelles with a well-defined size is a key requirement for cell function, yet our understanding of the underlying size control mechanisms is limited. While budding yeast cell polarization and