Focusing on cadherin-based adherens junctions, we address the functional and molecular architecture of these adhesions, including the mechanism of cadherin–cadherin interactions, the role of the cytoplasmic plaque in junction formation and signaling, and the critical role of the cytoskeleton in tissue ...
Cell–cell adhesions are inevitably exposed to mechanical forces. A landmark paper by Yonemura et al. identified how tension alters molecular function of the cadherin adhesion apparatus. Its legacy lies in the many on-going efforts to understand how mechanical force is used in cell–cell communicat...
(2014). Cell-cell adhesions and cell contractility are upregulated upon desmosome disruption. PLoS ONE 9:... Kaelyn,Sumigray,Kang,... - 《Plos One》 被引量: 9发表: 2014年 Focal adhesions, contractility, and signaling. Focal adhesions are sites of tight adhesion to the underlying ...
Homotypic cell-cell adhesions are mediated by cadherins, whereas adhesion between the cell and its extracellular matrix is mediated by integrins. Because cadherins and integrins comprise a wide variety of interactions at different levels, they are considered to be directly related elements that are ...
to cell–cell adhesions (Fig. 5), we hypothesized that mitotic microtubules should form more stable associations with the cell cortex at E-cadherin-dependent cell–cell adhesions than at non-adhesion sites. To test this, MDCK cells stably expressing mRFP-tagged EB1, which marked the plus ends...
Cell adhesions consist of multimolecular protein complexes of transmembrane adhesion receptors anchoring intracellular cytoskeletal structural proteins and... KM Yamada,B Geiger - 《Current Opinion in Cell Biology》 被引量: 1291发表: 1997年 Perspectives series: cell adhesion in vascular biology. Smooth mu...
n., plural: cell adhesions [sɛl ədˈhiːʒən] Definition: The binding of a cell to another cell or to an extracellular matrix component Table of Contents Cell Adhesion Definition Cell adhesionis theprocessin which acelluses a specialized complex of proteins to get connected and ...
Focal adhesions disassemble during mitosis, but surprisingly little is known about how these structures respond to other phases of the cell cycle. Three recent papers reveal unexpected results as they examine adhesions through the cell cycle. A biphasic response is detected where focal adhesions grow ...
Talking with force at cell–cell adhesions 中文标题 细胞间粘附力的对话 基本信息 发表日期:16_01_24 文章类型:News & Views 文章作者:Zoya Mann | Alpha S. Yap 原文链接:nature.com/articles/s41 关键词 cell–cell adhesion(细胞间粘附) cadherin(钙黏蛋白) mechanosensitivity(机械敏感性) mechanotransductio...
Cell Adhesions and Signaling: A Tool for Biocompatibility Assessment Cukierman E, Pankov R, Stevens DR, Yamada KM (2001) Taking cell matrix adhesions to the third dimension. Science 294:1708–1712 CrossRef Cukierman E... R Pankov,A Momchilova - 《Nato Science for Peace & Security》 被引量...