We have generated a pipeline that uses network graph theory to predict which BCR sequences within an immunosurveilling BCR clone perform cross-site immunosurveillance. These B cells tend to have higher BCR degree centrality but do not have the highest level of SHM within the clone. Therefore, ...
ph-ase theory phdchemical engineeri phinvdocsfor cycle ct phmagnoliifolia zhche pha phasor pha-responsive cell phach columbac phaenomenologie phaeoisariopsis pruni phaeolepiota aureapho phaethon lepturus phaethornis anthophil phage dna polymerase phagocytic reticular phagwa phahon yothin phak pua...
The study of Chinese herb inducing angiogenesis is supported by TCM theory of "activating blood to eliminate stasis" and "invigorating meridian and generating blood". Simiao yongan decoction (SMYA) was originally used for gangrene and we chose this decoction as the intervention to discover its ...
Intratumoural microbiota: from theory to clinical application Download PDF Review Open access Published: 28 June 2023 Intratumoural microbiota: from theory to clinical applicationHao Ji, Zhengting Jiang, Chen Wei, Yichao Ma, Jiahao Zhao, Fei Wang, Bin Zhao, Daorong Wang & Dong ...
Immune evasion is a hallmark of cancer [140]. According to the immunosurveillance theory, neoplastic cells can progress to generate clinically obvious cancer only if they escape from the control of immunological effector cells [141]. One study leveraged scRNA-seq data from 33 melanoma tumors and ...
Songsong Wang, Yilong Lin & Ziming Liu Department of Urology, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, 430061, Hubei, China Yan Li, Lang Guo, Haoyu Wang, Bingqi Zhang, Zhengming Liao & Zhongmin Zhang Hubei Key Laboratory of Theory and Application Research of Liver and...
nucleolar protein family A; TIN2, TERF1-interacting nuclear factor 2; TPP1, telomere protection protein 1; TRF1, telomeric repeat binding factor 1; TRF2, telomeric repeat binding factor 2; POT1, protection of telomeres 1; RAP1, TERF2-interacting protein. The telomere diagram is derived from...
Modern medicine divides the prostate into three main zones: peripheral zone (PZ), transition zone (TZ) and central zone (CZ) [72]. The theory of prostate zones has been widely applied and demonstrated since it was proposed. The differences in the pathogenesis, imaging features, histological fea...
[2]. This is the first application of phase separation theory to the field of biology, providing a new perspective for the in-depth study of the physicochemical mechanisms underlying the formation and function of membrane-free functional compartments in cells. Phase separation includes gas-liquid ...
The classical random network theory was introduced by Erdös-Rényi, based on the assumption that each pair of nodes (that is, constituents) in the network is connected randomly with probability p, leading to a statistically homogeneous network in which, despite the fundamental randomness of the ...