Unlike pseudotime algorithms, we infuse directionality by using RNA velocity to direct Markov chain edges (Extended Data Fig.1c). The RNA velocity vector of a given cell uses splicing dynamics to predict which genes are currently being up- or downregulated, and thus points towards the likely fut...
the radial gradient convergence (RGC) is estimated. Thus, in the case of eSRRF, this estimation is not just based on a set number of points at a specific radial
全部,细胞间通讯,细胞联系,细胞通讯,细胞间联系侦测,细胞胞间通讯 更多例句筛选 1. Theory of Qi may offer some insights to cell communication research, while cell communication allows Qi to see the essence . . . 气的理论可为细胞通讯研究提供启发,而从细胞通讯的角度有利于认识气的实质。 www.chemyq....
Dynamical systems theory A branch of classical physics that describes the dynamics of multiple variables (for example, molecular concentrations) in terms of a set of linear or non-linear differential equations. Entropy A generic term to quantify the amount of uncertainty associated with a system or...
scDNA intensities through simultaneously considering sparsity, noise, and cell heterogeneity, and adopted variational CBS for checkpoint detection. While after in silico experiment, we argue that those CBS approaches might not lead to an optimal segmentation result, some turning points might be masked....
Gene knockout experiments are straightforward methods to begin characterizing TF-target relationships in budding yeast. Nonessential TFs may be deleted and, in theory, their targets should have altered expression. This method had been used successfully to identify gene targets with altered expression upo...
The game that started it all, still a masterpiece even today. Maybe not as good as Pandora Tomorrow or Chaos Theory tho. Report Xbox IGN This is the kind of game I imagined when I used to dream about the experiences next generation consoles were going to give us. Splinter Cell is one...
The term “bifunctional theory” was coined to apply Gilman’s reaction pair concept to Pt rich alloy catalysts for methanol oxidation [4] (Eqs. (3–6)): Methanol adsorption (3)Pt+CH3OH→Pt-(CH3OH)ads C–H bond activation (4a)Pt-(CH3OH)ads→Pt-(CH3O)ads+H++e− (4b)Pt-(CH3...
The current theory of coacervation posits that phase separation is driven by forces generated by weak electrostatic and hydrophobic interactions between amino acid side chains and interacting biomolecules. In this study, we demonstrated senescence-associated formation of protein condensates in the nuclei of...
developed the theory. G.D. performed the patch-clamp work under the supervision of J.T.R.; G.D. and J.T.R. also prepared the text for that section. V.G.-L., G.W., R.P. and J.M.T. wrote the manuscript. All authors read and approved the manuscript. Corresponding authors ...