A particularly diverse group of diseases result from direct or indirect disruption of desmosomes—a consequence of their importance in tissue integrity, their extensive distribution, complex structure, and the wide variety of functions their components accomplish. As a consequence, disruption of desmos...
Characterizing noise structure in single-cell RNA-seq distinguishes genuine from technical stochastic allelic expression Single-cell RNA-sequencing (scRNA-seq) facilitates identification of new cell types and gene regulatory networks as well as dissection of the kinetics of g... JK Kim,AA Kolodziejc...
Capillary-like structure formation by HUVECs was recorded using a Zeiss inverted microscope. The Image J was used to quantify thetubelength40. Luciferase activity To verify the direct interactions between MALAT1 and miR-497, the hMALAT1 cDNA full length (8779 bp) was cloned into psiCHECK2 ...
CAR structure CAR T cell engineering Intracellular signaling pathways of the CARs Recognition of the tumor-associated antigens, expression level, and susceptibility to CAR T cells CAR T cell therapy in solid tumors: recent advances Challenges of CAR T cell therapy for solid tumor Future directions ...
One essential structure that needs to scale to maintain the robust segregation of chromosomes during early embryogenesis is the mitotic spindle. Spindles can scale an order of magnitude and fall into what appears to be a universal scaling relationship with cell size [4, 5, 6, 7, 8, 9, 10,...
Drug-induced changes of cytoskeletal structure and mechanics in fibroblasts: an atomic force microscopy study. Biophys J. 2000;78(1):520–35. Article PubMed PubMed Central CAS Google Scholar Baghaei K, Hashemi SM, Tokhanbigli S, Asadi Rad A, Assadzadeh-Aghdaei H, Sharifian A, Zali MR...
5). In addition, the tissue structure of 5HRE-NGF-NSCs was clear and natural. In Nissl staining, amongst the four treated groups, the quantity of Nissl+ cells in the NGF-NSCs and 5HRE-NGF-NSCs groups was higher; therein, NGF-5HRE-NSCs was the better. These results indicated that 5...
,A.,Khan 摘要: This paper summarizes studies on antibody formation in the bone marrow and the suppressive effects of intravenous immunization with allogeneic blood cells on T-cell function in mice. The latter studies were extended by employing the limiting dilution culture system developed in Ivan ...
& Peng, Y. PDLIM1: Structure, function and implication in cancer. Cell Stress 5(8), 119–127 (2021). Article CAS PubMed PubMed Central Google Scholar Huang, Z. et al. PDLIM1 inhibits tumor metastasis through activating hippo signaling in hepatocellular carcinoma. Hepatology 71(5), 1643...
TST, known as thiopeptide, possesses anticancer properties, and its chemical structure is shown in Fig. 1A. Pancreatic cancer cells have a strong ability to proliferate; therefore, we first evaluated the inhibitory effect of TST on cell proliferation. Using the CCK-8 assay, we measured the viab...