Single-cell transcriptome sequencing of B-cell heterogeneity and tertiary lymphoid structure predicts breast cancer prognosis and neoadjuvant therapy efficacy. Clin Trans Med. 2023. https://doi.org/10.1002/ctm2.1346. Article Google Scholar Meylan M, Sautes-Fridman C, Fridman WH. Tertiary lymphoid ...
The results of Dmax in the 1st and 11th size class and Dmean in the 12th size class are not very reliable. In class 11 and 12, in general, higher numbers of cells were shown for the lower disintegration times, while in the regression method used, the results obtained for the largest ...
This model of cancer cell structure and response, which we call NeST-VNN, allowed for three binary input features per gene, describing the presence or absence of point mutation/insertion/deletion, copy number amplification (CNA) or copy number deletion (CND) (Fig. 1b and Methods). These ...
they can be used to link between in vitro properties of cell class and in vivo EAPs. We asked whether the experimentally measured intrinsic properties of the actual cells each model represents differentiate between morphology class AP and SP. Comparison between in vitro cellular data used to develo...
(11.7 Å resolution) of ribosomes from cryo-tomograms of putative lokiarchaeal cells (large-subunit proteins (LSU), blue; small-subunit proteins (SSU), orange; rRNA, white). Middle, secondary structure prediction of the ‘Ca.L. ossiferum’ large-subunit rRNA (expansion segments ES9/ES...
In transformed cancer cells, mitosis proceeds with little regard for cellular checkpoints, resulting in nucleotide addition mistakes during the S-phase, as well as lesions in the structure. This results in the activation of the DDR cellular pathway, which is responsible for the identification and ...
Mougous JD, Petzold CJ, Senaratne RH et al (2004) Identification, function and structure of the mycobacterial sulfotransferase that initiates sulfolipid-1 biosynthesis. Nat Struct Mol Biol 11:721–729. https://doi.org/10.1038/nsmb802 Article CAS PubMed Google Scholar Movahedzadeh F, Smith DA...
public class HealthSystem : ISystem { public World World { get; set; } private Filter filter; private Stash<HealthComponent> healthStash; public void OnAwake() { this.filter = this.World.Filter.With<HealthComponent>().Build(); this.healthStash = this.World.GetStash<HealthComponent>(); } ...
11, 6299 (2020). Article CAS PubMed PubMed Central Google Scholar Sikic, B. I. et al. First-in-human, first-in-class phase I trial of the anti-CD47 antibody Hu5F9-G4 in patients with advanced cancers. J. Clin. Oncol. 37, 946–953 (2019). Article CAS PubMed PubMed Central ...
1). OnClass is a Python-based open source package able to compute cell type similarities between the hierarchical structure of existing cell ontologies, such as the Cell Ontology25 and the Allen Ontology20,33. Moreover, we provide a pre-trained model, which given an input gene expression ...