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13,14,15. Considering paired cases only and using a paired test, we found a significant increase in the percentage of MES cells per patient on average at recurrence (Fig.3a). This MES shift was also observed in our bulk RNA-seq data (Extended Data Fig.3a). While we found no significan...
Achieving cost-competitiveness remains challenging for industrial biomanufacturing. With whole-cell biocatalysis, inefficiency presents when individual cells vary in their production levels. The problem exacerbates when the basis for such production hete
Hi-Wire Brewing sustained major damage at its River Arts District location in the Asheville area. Bryna Frosaker, owner and chief people officer of Hi-Wire said all of their employees are safe but the physical damage will take time to repair. A timeline on when power and water will return...
Wound repair: role of immune–epithelial interactions. Mucosal Immunol. 8, 959–968 (2015). Article CAS PubMed Central Google Scholar Clark, A. G. & Vignjevic, D. M. Modes of cancer cell invasion and the role of the microenvironment. Curr. Opin. Cell Biol. 36, 13–22 (2015). ...
MGMT is a DNA repair enzyme that removes alkyl and methyl adducts formed at the O6 position of guanines, thereby antagonising the lethal effects of alkylating agents like TMZ. MGMT protein expression is under epigenetic control, meaning that the methylation of its promoter results in the silencing...
Stem cell therapy in Los Angeles is an innovative medical treatment that harnesses the power of stem cells to repair and regenerate damaged or diseased tissues in the body. Stem cells are unique cells that have the remarkable ability to develop into various specialized cell types, such as bone,...
One of the best ways to ensure that our therapies have the best effect on you is to keep a healthy diet. Your diet directly provides the nutrients and materials your cells use to grow, divide, and repair. There are added benefits to eating low-calorie because you put less weight and, ...
which ensure epithelial repair and self-renewal; Paneth cells, interspersed among ISCs, which contribute to ISCs turnover and secrete antimicrobial peptides; +4 position cells, relatively quiescent stem cells with protective roles towards Lgr5+ ISCs damage; and transit-amplifying (TA) cells that inh...
Mesothelial cells form the mesothelium, a simple epithelium lining the walls of serous cavities and the surface of visceral organs. Although mesothelial cells are phenotypically well characterized, their immunoregulatory properties remain largely unknown