which tended to activate at different points during the trial (Fig.2f). We quantified this difference by computing the correlation in activity between single cells. Activity was more strongly correlated among Ss
We present the Python package CELL, which provides a modular approach to the cluster expansion (CE) method. CELL can treat a wide variety of substitutional systems, including one-, two-, and three-dimensional alloys, in a general multi-component and mult
In almost all work to date, it has been assumed that the two definitions are equivalent, meaning that the stress and shape axes are tightly coupled17,22–24. Under this assumption, differences between the axes of stress and shape would be modest and attributable to biological noise. Here we...
The somata of amacrine cells lie mainly within the proximal portion of the inner nuclear layer (INL), but those of many subtypes are displaced to theganglion celllayer (GCL) or lie within the IPL. In some retinas, displaced amacrine cells even outnumber theganglion cellsin the GCL. On the...
Fig. 3: Translation inhibition as a reference to predict pathways causal to persistence. a, Wild-type cells in tetracycline are highly antibiotic-tolerant but become susceptible after tetracycline is removed. Survival of cells in or after tetracycline is higher than for untreated cells (one-sided ...
containing large data sets with several thousand dimensions (features). Dimension reduction methods (such as PCA) do not provide satisfactory results, and also obscure the meaning of the original attributes in the data. For the constructed models to be usable, they must fulfill the requirement of...
Then, for each cell, a label was transferred by reference mapping [36] using Seurat. In the case of the 10XPBMC dataset, an annotated PBMC reference dataset [40] was utilized for label transfer. As for the Chen2019 dataset, the scRNA-seq data of the adult mouse brain from the Allen ...
resides. this means we could not use the ground truths for reference construction. instead, we use the single- and upper-level regions that are detected during initial segmentation as references. we use these references by first creating a distance profile per reference, and computing the ...
To highlight the advantages of storing boundary data in boundary face-based arrays as opposed to total face-based arrays, let us consider an example where we are interested in computing the area-weighted average of a certain scalar, ϕ, at the boundary of the entire computational domain. Mat...
HRT atlas v1.0 database Redefining human and mouse housekeeping genes and candidate reference transcripts by mining massive RNA-seq datasets. Nucl Acids Res. 2021;49(D1):947–55. 41. Risso D, Ngai J, Speed TP, Dudoit S. Normalization of RNA-seq data using factor analysis of control ...