Biolabs also developed an accurate and robust tumor cell proliferation inhibition assay service to support global clients in evaluating several immune checkpoint-related (such as PD-1, TIM-3, LAG-3, TIGIT, OX40, GITR, etc.) biologic or small molecules in inhibition of tumor cell proliferation....
proliferate. The ERK inhibitorU0126, added 20min prior to EGF, inhibited both peaks of the translocation of ERK as well as goblet cell proliferation. Interestingly, inhibition of the second peak of ERK translocation with U0126 also prevented EGF-stimulated proliferation. In addition to the ...
Inhibition of T-cell proliferation is the most common approach to assess human myeloid-derived suppressor cell (MDSC) functions. However, diverse methodologies hinder the comparison of results obtained in different laboratories. In this chapter, we present a T-cell proliferation assay procedure based ...
Contact inhibition controls cell survival and proliferation via YAP/TAZ-autophagy axis At high cell density or when plated on soft matrix, YAP/TAZ are redistributed from the nucleus to the cytosol, becoming transcriptionally inactive. Here the authors show that at high cell density, autophagosome for...
wound healing and transwell migration assays were performed to characterize the roles of SHED-Exos on cell proliferation, apoptosis and migration of human umbilical vein endothelial cells (HUVECs). The anti-angiogenic activit...
EZ4U – Cell Proliferation Assay Product Overview The EZ4U kit is a two to five-hour test for the measurement of cell proliferation and cell toxicity. The EZ4U test employs non-toxic tetrazolium salts, which are reduced to colored formazan. As this reduction process requires functio...
Nystrom ML, McCullogh D, Weinreb P, Violette S, Speight PM, Marshall JF, Hart IR, Thomas GJ (2006). COX-2 inhibition suppresses αvβ6 integrin-dependent oral squamous carcinoma invasion.Cancer Res.66, 10833–42. Froeling, F. E., Mirza, T. A., Feakins, R. M., Seedhar, A.,...
This assay has extensive utility for the evaluation of cell metabolic activity by which the viability of the cell can be inferred. The reduction in the number of viable cells may result from two major processes—inhibition of cell metabolism and/or proliferation (cytostatic effect) or actual cell...
cell proliferation assay, which provides a superior alternative to bromodeoxyuridine (BrdU) or3H-thymidine incorporation methods for measuring new DNA synthesis. Alternatively, our CyQUANT Cell Proliferation Assay Kits use the CyQUANT ...
PrestoBlue HS Cell Viability Reagent is an improved version of PrestoBlue reagent, containing highly purified resazurin, which increases sensitivity and reduces background in cell proliferation assays. Add the power of multiplexing with reagents such as the CyQUANT Direct assay to improve your data ...