Members of the FW2.2 gene family in corn (Zea mays) have been named CNR (Cell Number Regulator) and two of them exert their effect on organ size by modulating cell number. Due to the critical roles of FW2.2/CNR genes in regulating cell number and organ size, this family provides an ...
Cell Number Regulator1 Affects Plant and Organ Size in Maize: Implications for Crop Yield Enhancement and Heterosis. KE, Howard RJ, Hou Z, Simmons CR: Cell number Regulator1 affects plant and organ size in maize: implications for crop yield enhancement and heterosis... Mei,Guo - 《Plant Cell...
The Cyclin-dependent kinase 1: more than a cell cycle regulator Article Open access 28 October 2023 The two sides of chromosomal instability: drivers and brakes in cancer Article Open access 29 March 2024 References Kops, G. J. P. L., Foltz, D. R. & Cleveland, D. W. Lethality...
Machine learning uncovers cell identity regulator by histone code Bo Xia, Dongyu Zhao, Guangyu Wang, Min Zhang, Jie Lv, Alin S. Tomoiaga, Yanqiang Li, Xin Wang, Shu Meng, John P. Cooke, Qi Cao, Lili Zhang & Kaifu Chen Nature Communications volume 11, Article number:...
The study found that MSI1 as a stem gene in colorectal cancer cells is a key regulator of CD44+ CSC development and enhances tumor stem cell therapy resistance by triggering the formation of anti-apoptotic stress granules (SGs) [111]. FANG’s study showed that MSI2 can up-regulate the ...
Outlier cell with library size and number of expressed genes more than 3 median absolute deviations (MADs) below the median value, unique molecular identifiers (UMIs) counts under 10,000 or greater than 500, and detected genes under 4100 or greater than 200 were removed. Low abundance genes ...
FOXM1 is a crucial regulator of many biological processes and tissues, and dysregulation of FOXM1 can significantly contribute to tumorigenesis and cancer progression. For its potential as a target for cancer therapies, FOXM1 was named the Molecule of the Year in 2010 [106]. Over the past few...
(Fig.2g; Table S7), which was a known regulator of metabolism. Lastly, Cell-cycle-related regulons (MYBL2 and E2F2) were highly enriched in pCAF (Fig.2g; Table S7). The metabolic correlation of meCAFs prompted us to perform SCPA analysis to study their metabolic pathway activity. As ...
(b). Velocyto does not compute fate probabilities. Gene expression trends for the beta-regulatorPdx134,70,71(c). On thexaxis is the pseudotime used by the corresponding method, on theyaxis is gene expression. For FateID51, thexaxis is given by the cell indices, which are assigned to ...
Each RGM is represented by its involving driver regulator and the number of its regulated genes is given in parentheses. Genes in bold indicate the top-20 driver regulators associated with Fig. 4j. f The identified out-degree type of RGM involving PRDM1...