Cells communicate with each other through secreting and releasing proteins and vesicles. Many cells can migrate. In this study, we report the discovery of migracytosis, a cell migration-dependent mechanism for releasing cellular contents, and migrasomes,
et al. Apoptotic cells induce migration of phagocytes via caspase-3-mediated release of a lipid attraction signal. Cell 113, 717–730 (2003). Article CAS PubMed Google Scholar Suzuki, J., Denning, D. P., Imanishi, E., Horvitz, H. R. & Nagata, S. Xk-related protein 8 and CED-...
We found the signaling pathways like Nicotinamide Phosphoribosyltransferase-Insulin (VISFATIN), Angioprotein (ANGPT), Secreted Phosphoprotein 1 (SPP1), and Macrophage Migration Inhibitory Factor (MIF) pathways with large distance in biological functions, while VISFATIN, Galectin 9 (GALECTIN), Interferon-...
proteomic, and chromatin accessibility profiles. Functionally, these iMG exhibit Ca2 + transients, cytokine driven migration, immune responses to inflammatory signals, and active phagocytosis of CNS related substrates including synaptosomes, amyloid beta and myelin. Significantly, the toolkit...
apposed cell surfaces in desmosomes and form the basic adhesive unit of desmosomes [38]. LAMA3 binds to its high-affinity receptor and mediates the attachment and migration of cells [39]. Different from short-range interactions, long-range interactions have distinct spatial distributions. For ...
Mrass P, Weninger W (2006) Immune cell migration as a means to control immune privilege: lessons from the CNS and tumors. Immunol Rev 213:195–212 Article PubMed Google Scholar Fisher DT, Chen Q, Appenheimer MM, Skitzki J, Wang WC, Odunsi K, Evans SS (2006) Hurdles to lymphocyte...
Definition and composition of the SASP Regulatory mechanisms of the SASP Through the NF-kB signalling pathway Through the DNA damage reaction Through the p38MAPK signalling pathway Through the m-TOR pathway Through the cGAS-STING signalling pathway Effect of the SASP on atherosclerosis through inflammat...
S3C). Compared with BM, circulating myeloma cells from this patient exhibited high expression of genes that correlated with disease aggressiveness and cell migration (Additional file 1: Fig. S3D), which may explain their presences in circulation. Identification of inter- and intral-tumor ...
3D bioprinting or electrospinning), to cell guiding approaches, where either biochemical signals, mechanobiological cues or a spatial inhomogeneity of the scaffold’s material properties, are responsible for the preferential migration and sprouting of endothelial cell co-cultures12,25,26,27,28,29,30....
These cells were enriched for genes associated with negative regulation of mesenchymal cell migration (Supplementary Table 9), reinforcing Zfp281’s putative role in mesenchymal fate specification. Additionally, they were depleted for expression of both off-target and on-target markers genes from day ...