or internal balance, through efficient and tireless transport mechanisms that make the membrane a sort of microscopic customs official, allowing and denying the entry and exit of ions and molecules in accordance with the cell's real-time needs.Cell...
A new aspect of cell membrane structure is presented, based on the dynamic clustering of sphingolipids and cholesterol to form rafts that move within the fluid bilayer. It is proposed that these rafts function as platforms for the attachment of proteins when membranes are moved around inside the...
The cell membrane – also called the plasma membrane or cytoplasmic membrane – is among the most fascinating and elegant constructs in the world of biology. The cell is considered the fundamental unit or "building block" of all living things on Earth; your own body has trillions of them, an...
Cell membrane fractions were not contaminated with supernatant DT-diaphorase, but were contaminated by mitochondrial fraction in both normal and CCl4-treated rats to some extent. Glucose-6-phosphatase activity and RNA content of the normal membrane fraction were 9 % and 6 % of microsomes, ...
Bridging the gap: membrane contact sites in signaling, metabolism, and organelle dynamics. J. Cell. Biol. 205, 759–769 (2014). CAS PubMed PubMed Central Google Scholar Helle, S. C. et al. Organization and function of membrane contact sites. Biochim. Biophys Acta 1833, 2526–2541 (...
In order to achieve this function, cell membranes contain embedded membrane proteins that play different roles. Several of families of membrane proteins have been identified, such as (1) channels and pores which control the exchange of ions and water between the inside and outside of the cell ...
Kappa- but not delta-opioid receptors mediate effects of ischemic preconditioning on both infarct and arrhythmia in rats. Features two experiments which determined the role of kappa- and delta-opioid receptors in cardioprotection of ischemic preconditioning in rat heart. Mater... Wang,Guan-Ying,Wu,...
11月7日,Cell Press(细胞出版社)期刊《Cell Reports Methods》在线发表题为“Opto-chemogenetic inhibition of L-type CaV1 channels in neurons through a membrane-assisted molecular linkage”的研究论文。该工作由北京航空航天大学生物...
plasma membrane was broadly accepted and, even then, the fluid mosaic model did not prevail until the 1970s. How were the cell boundaries considered between the articulation of the Cell Theory around 1839 and the formulation of the fluid mosaic model that has described the cell membranes since ...
inducing membrane curvature and/or bridging membranes. The simulations show that synaptotagmin-1 C2-domains placed near the site of fusion hinder the ability of SNARE complexes to bring the membranes together and induce fusion, supporting alternative models whereby synaptotagmin-1 acts remotely to accele...