We present Building Aggregates with a Neighborhood Kernel and Spatial Yardstick (BANKSY), an algorithm that unifies these two spatial clustering problems by embedding cells in a product space of their own and the local neighborhood transcriptome, representing cell state and microenvironment, respectively...
We’ll name that range Sales . Now we can easily calculate total sales by entering the formula =SUM(Sales) in E7. The Sales range is absolute, meaning it always refers to $B$2:$D$6. Exhibit 5 Creating month and region subtotals requires the use of relative references. Let’s start ...
The procedure is described in Table 1. Table 1 Synthetic data generation. Full size table Meaning that for every spatial capture location (s) we first sample the number of cells (Cs) contributing to this, and the number of types (∣Zs∣) which these cells may belong to. lb and ub ...
acalm yourself的意思 calm yourself meaning[translate] athe visual character of the Nile Valley influenced the architects to create an architecture that could stand up against the scale and grandeur of the great Nile River 尼罗谷的视觉字符影响建筑师创造可能反对伟大的尼罗河的标度和伟大的建筑学[translat...
Edge detection: This technique is based on the assumption that one edge in an image is belonged to an extreme change in image intensity (Gonzalez and Wintz, 1977). Edge detection often supplies effective outcomes for images with “good boundaries” meaning that intensity of changes is severe thr...
A unique feature of cell surface protein–carbohydrate interactions is that they are usually multivalent—meaning that there are multiple carbohydrates interacting with a single protein at multiple identical binding sites simultaneously... Zhang,Zhongsheng - 《Methods in Enzymology》 被引量: 2发表: 2003...
Changes in the epigenetic regulation of gene expression have a central role in evolution. Here, we extensively profiled a panel of human, chimpanzee, gorilla, orangutan, and macaque lymphoblastoid cell lines (LCLs), using ChIP-seq for five histone marks,
For example, the acne lesions of the patient in Fig. 4 are on both sides of the face, meaning the user needs to take two profile photos and mark the lesions areas as regions of interest (ROIs). The diagnosis results can be obtained after several minutes, which show that (1) the ...
locally, whereas CellRank aggregates these local signals globally, computing longer range trends. The single-cell field has reached a consensus that clustering cells in 2D or 3D representations must be avoided32and, similarly, we argue that velocity vectors projected onto two or three dimensions ...
During the goal-directed navigation task, Sst44 cells tended to activate in unison in contrast to other Sst and non-Sst cells, which tended to activate at different points during the trial (Fig.2f). We quantified this difference by computing the correlation in activity between single cells. Ac...