we then concatenated the scores (predicted probabilities) of all folds, and computed an AUC value with R packagepROC.The lambda value with the greatest AUC was selected as the optimal parameter to retrain a final logistic lasso model using all TCGA LIHC samples. ...
Summarization of gene level was performed using the SST-RMA method and genome version hg38 (Homo Sapiens). The background was adjusted by a quantile normalization and a log2 data transformation. The significant genes were ranked by ANOVA p value <0.05. Heat maps represent z-scores based on ...
Notably, ZBED2 has recently been associated with basal identity in keratinocytes [54] and regulation of inflammation in pancreatic cancer [55]. Combining analyses of tumour and cell line SEs should avoid the identification of master TFs expressed by the stroma. In fact, we found that TFs ...
Interestingly, exosomes derived from a mouse neuroblastoma cell line or from human cerebrospinal fluid can counteract the synaptic-plasticity-disrupting activity of both synthetic and AD brain-derived Aβ peptide. The effect seems to be due to absorption of Aβ on the exosome surface (where it ...
Two phases of basal recording of twenty minutes each were acquired before performing the single cell ablation to verify whether the neural nMeotlewcuolesr2k01u6,n21d, e10r18investigation presented stable activity (see Methods for criteria o4 fofs1t7ability), and to dwihsectahredr theexpneeurr...