or “overlapping with multiple loci”. Finally, we assessed the presumed functional categorization (biotypes) of novel isoforms. We found that 42% are protein-coding, more than the 36% of protein-coding isoforms found in the GENCODE database (...
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where it modulates excitation/contraction coupling26, its function in T cells has not been reported. Using a pooled shRNA screen to identify ion channels that regulate T cell responses to viral infection in vivo, we find that deletion ofCacnb1impairs...
A.R. is a cofounder and equity holder of Celsius Therapeutics, an equity holder of Immunitas and was an SAB member of Neogene Therapeutics, Thermo Fisher Scientific, Asimov and Syros Pharmaceuticals until 31 July 2020. Since 1 August 2020, A.R. is an employee of Genentech, a member of ...
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Recent advances in single cell technology have enabled dissection of cellular heterogeneity in great detail. However, analysis of single cell DNA sequencing data remains challenging due to bias and artifacts that arise during DNA extraction and whole-gen
If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creative...
If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creative...