et al. Cell free DNA testing-interpretation of results using an online calculator. Am J Obstet Gynecol 213(1), 30 e31-34 http://www.med.unc.edu/obgyn/Patient_Care/specialty-services/maternal-fetal-medicine/mombaby/nips_calc.html (2015).Grace MR, Hardisty E, Green NS, et al. Cell ...
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Obstet Gynecol Surv 2016;71(3):146-147 One of the most important technical advances in prenatal care in recent times is analysis of cell-free DNA (cfDNA) in the maternal plasma to screen for fetal aneuploidy. Use of cfDNA screening for aneuploidy was clinically introduced in 2011 in the Uni...
A new type of prenatal screening however, offers parents-to-be a better option. Cell-Free Fetal DNA testing detects chromosomal abnormalities through a simple blood test that is more accurate than current screening tests and can be done earlier in pregnancy—as early as the 10th week, with res...
Circulating cell-free DNA (cfDNA) assays for monitoring individuals with cancer typically rely on prior identification of tumor-specific mutations. Here, we develop a tumor-independent and mutation-independent approach (DELFI-tumor fraction, DELFI-TF) using low-coverage whole genome sequencing to determ...
Table 2 Adherence of cell-free DNA noninvasive prenatal screening tests to laboratory recommendation in ACMG position statement Full size table Recommendation 1 [Common Aneuploidy] Laboratories should provide readily visible and clearly stated detection rate (DR), specificity (SPEC), positive predictive ...
Cell-Free DNA BCT is a direct-draw venous whole blood collection device intended for the collection, stabilization and transport of venous whole blood samples for use in conjunction with cell-free DNA next generation sequencing assays that have been cleared or approved for use with samples collected...
100-tube box (10.0 mL) – 16mm x 100mm, CE 230656 1000-tube case (10.0 mL) – 16mm x 100mm, CE 230657 **Not for Clinical Diagnostic Use. USA customers click here. Order Cell-Free DNA BCT RUO & CE today Request a quote International customers find a distributorCitation...
Abstract Importance Cell-free DNA (cfDNA) tests are increasingly being offered to women in the first trimester of pregnancies at a high risk of trisomy 21 to decrease the number of required invasive fetal karyotyping procedures and their associated miscarriages. The effect of this strategy has not...
An updated cell-free DNA algorithm blinded to the pregnancy outcome was also assessed. Results A total of 20,194 women were enrolled at a median gestational age of 12.6 weeks (interquartile range, 11.6–13.9). The genetic outcomes were confirmed in 17,851 cases (88.4%): 13,043 (73.1%) ...