Cancer is a group of diseases in which cells divide continuously and excessively. Cell division is tightly regulated by multiple evolutionarily conserved cell cycle control mechanisms, to ensure the production of two genetically identical cells. Cell cyc
Thus, there is clear evidence that methods based on the use of physiological probes cannot directly address cell division but only the presence of some active functions or the integrity of cell structures. Therefore, cells in which any kind of metabolic activity can be detected should be called ...
Meanwhile, genes involved in cell differentiation and cell division, such as FLA2 (Ghir_A07G020700), were found in Jin3 and TM3 clusters, suggesting that Jin3 and TM3 clusters may be xylem parenchyma cells. Further analysis of the enriched genes related to cell cycling and to the development...
High-grade glioma is the most common and aggressive primary brain tumor in adults with poor therapeutic efficiency and survival prognosis. Cell division cycle associated 8 (CDCA8) has been well known as a cell cycle regulator and tumor promotor in variou
“double handshake” provides a fail-safe mechanism to prevent inappropriate activation of these highly active effector cells (Fig. 2-12). Signal transduction mediated through CD3 and other peptides associated with the TCR initiates cytokine synthesis to trigger division of the activated T cells (IL...
The division cycle of the nucleated planctomycete G. obscuriglobus appears to be a complex process in which chromosomal DNA is transported to the daughter cell bud after initial formation of the bud, and this can be performed repeatedly by a single mother cell. Conclusion The division cycle ...
Stem cell functional division Whole-body development During division, the presence of different stem cells depends on organism development. Somatic stem cell ESCs can be distinguished. Although the derivation of ESCs without separation from the TE is possible, such a combination has growth limits. Bec...
various histones with direct effect on DNA-packaging were found downregulated and thus influence DNA-replication. Further, the elongation factorEIF5AL1[45] was found exclusively downregulated by AraC + IDEL in RS4;11. Both mechanisms show a specific enhancement of cell division critical check-...
7. Furthermore, HSCs differ in their proliferative capacity, which influences self-renewal kinetics8,9, with some HSCs generating specific blood cells without undergoing cell division10. Single-cell sequencing analysis confirmed that adult HSCs are a heterogeneous mixture of haematopoietic stem and ...
Fig. 7: Biased inheritance of RNA following asymmetric cell divisions from 16- to 32-cell stage. a Symmetric cell division of dividing 16- to 32-cell stage embryo labelled for RNA and Membrane-GFP. b RNA intensity profiles from 16-cell stage mother cells (pre-division) to outer 32-cell ...