16.2. Tryptamine role in cytotoxicity: necrosis, apoptosis, autophagy, and vesicles There are various pathways to cell death and cell survival in the cell death diseases including Alzheimer disease (AD). Cell death occurs primarily in two forms: passive and programmed. Passive cell death, or necro...
(2006) Neuronal cell death in Alzheimer's disease and a neuroprotective factor, humanin. Curr. Neuropharmacol. 4, 139-147.Niikura T, Tajima H, Kita Y. Neuronal cell death in Alzheimer's disease and a neuroprotective factor, humanin. Curr Neuropharmacol 2006; 4:139-1347....
《Cell Death Dis.》:老药新用 阿尔茨海默症(Alzheimer’s Disease, AD)是一种中枢神经退行性疾病,又称为老年痴呆,是几种痴呆症中占比最大的一种,给患者和其家庭带来极大的痛苦,但至今没有十分有效的治疗药物和治疗手段。研究发...
authors have suggested that apoptosis occurs in Alzheimer's disease. However, the present investigations of our and many other laboratories found only necrotic morphology of ISEL- and TUNEL-positive neurons in Alzheimer's disease, which agrees with the known time kinetics of apoptotic cell death. As...
代谢病研究所和上海交通大学BIO-X研究院单畅博士、张登硕士、马冬霓博士,以及杨毓莹博士、李胜天教授和刘建民教授等合作在Cell Death Discovery上发表了题为“Osteocalcin ameliorates cognitive dysfunctions in a mouse model of Alzheimer’s Disease by reducingamyloidβ burden and upregulating glycolysis in neuroglia...
Cell death in Alzheimer\"s disease evaluated by DNA fragmentation in situ H Lassmann,C Bancher,H Breitschopf,... 被引量: 0发表: 1995年 Endothelial cell and hepatocyte deaths occur by apoptosis after ischemia-reperfusion injury in the rat liver. Apoptosis was determined by DNA fragmentation as...
2023年8月25日,中国科学院大学生命科学学院郎明林教授课题组在Nature子刊Cell Death Discovery(IF=7.127)发表了题为“New insight into protein glycosylation in the development of Alzheimer’s disease”的研究综述。综述总结了目前发现的AD细胞中一些重要蛋白糖基化模式改变的情况,介绍对于蛋白质糖基化影响AD产生机制...
In this review, we will discuss the Aβ induced integrin/FA signaling pathways that mediate cell cycle activation and cell death. 展开 关键词: Integrin FAK Paxillin Cyclin D1 Alzheimer's disease Cell cycle DOI: 10.1016/j.bbadis.2006.11.007 被引量: 101 ...
Cell Death Dis︱暨南大学陈孝银/张力团队合作揭示运动锻炼缓解高脂饮食诱导的抑郁样行为的机制 找实验方法,上脑声常谈 撰文︱作者课题组 责编︱王思珍 长期高脂饮食(High-fat diet,HFD)不仅可导致机体代谢功能障碍,还可诱发多种情感障碍和认知缺陷[1,2],但其引起的神经行为改变的生物学机制尚未完全阐明。值得注意...
in complex ways. A pair of Herpesviruses--HHV 6A and 7--were found in greater abundance in brain samples from AD patients compared with normal brains. These viruses seem to also be implicated in the AD-related genetic networks responsible for classic Alzheimer's pathology, including cell death...