Popescu BO, Ankarcrona M (2004) Mechanisms of cell death in Alzheimer's disease: Role of presenilins. J Alzheimers Dis 6, 123-128.Popescu BO, Ankarcrona M (2004) Mechanisms of cell death in Alzhe- imer's disease: role of presenilins. J. Alzheimers Dis. 6, 123-128....
16.2. Tryptamine role in cytotoxicity: necrosis, apoptosis, autophagy, and vesicles There are various pathways to cell death and cell survival in the cell death diseases including Alzheimer disease (AD). Cell death occurs primarily in two forms: passive and programmed. Passive cell death, or necro...
Diseases articles withinCell Death & Disease Featured Article 22 May 2025|Open Access Asb10 accelerates pathological cardiac remodeling by stabilizing HSP70 Ke Lin ,Wenjie Wei &Qinfeng Li Article 20 May 2025|Open Access Cellular crosstalk mediated by Meteorin-like regulating hepatic stellate cell activa...
Deep transfer learning approach for automated cell death classification reveals novel ferroptosis-inducing agents in subsets of B-ALL Paweł Stachura ,Zhe Lu &Aleksandra A. Pandyra Article 17 May 2025|Open Access Prolyl 4-hydroxylase subunit alpha-2 acts as a TRIM21 ubiquitination substrate to pro...
《Cell Death Dis.》:老药新用 阿尔茨海默症(Alzheimer’s Disease, AD)是一种中枢神经退行性疾病,又称为老年痴呆,是几种痴呆症中占比最大的一种,给患者和其家庭带来极大的痛苦,但至今没有十分有效的治疗药物和治疗手段。研究发...
2022年8月20日,华中科技大学同济医学院基础医学院病理生理学系王小川教授团队在Cell death and disease杂志上发表了题为“USP10 deubiquitinates Tau, mediating its aggregation”的研究论文。该研究发现USP10作为Tau去泛素化酶,调控Tau去泛素化并促进Tau磷酸化,参与毒性Aβ介导Tau聚集的调控机制,对AD的发病提供新线索...
Provides information on Alzheimer's diseases. Expectation on the increase in Alzheimer's disease cases in the U.S. by 2050; Findings on the brain tissue samples of Alzheimer's victims; Efforts of scientists Leslie Wilson and Stuart Feinstein to understand microtubles, long thin filaments that ...
2023年8月25日,中国科学院大学生命科学学院郎明林教授课题组在Nature子刊Cell Death Discovery(IF=7.127)发表了题为“New insight into protein glycosylation in the development of Alzheimer’s disease”的研究综述。综述总结了目前发现的AD细胞中一些重要蛋白糖基化模式改变的情况,介绍对于蛋白质糖基化影响AD产生机制...
Alzheimer's disease Apoptosis Cell Death Encephalopathy Microglial Cells Neurodegeneration Clinical Manifestations Human immunodeficiency virus type-1 (HIV-1) infection is the commonest cause of dementia in adults less than 40 years of age. Prior to the availability of combination antiretroviral therapy, ...
Many patients infected with human immunodeficiency virus type-1 (HIV-1) suffer cognitive impairment ranging from mild to severe (HIV dementia), which may result from neuronal death in the basal ganglia, cerebral cortex and hippocampus. HIV-1 does not kill neurons by infecting them. Instead, vira...