Cell Death Discovery is a multidisciplinary, international, online-only, open access journal, dedicated to publishing research at the intersection of medicine with biochemistry, pharmacology, immunology, cell biology and cell death, provided it is scientifically sound. The unrestricted access to research ...
2024Cell Death Discovery doi:10.1038/s41420-024-02253-3pmid:39622791 Helicobacter pylori (H. pylori) is a gram-negative pathogen that colonizes gastric epithelial cells, and its chronic infection is the primary risk factor for the development of gastric cancer (GC). Ferroptosis is an iron-depende...
FOXA1 (Forkhead Box A1) and FOXA2 (Forkhead Box A2) serve as pioneering transcription factors that build gene expression capacity and play a central role in biological processes, including organogenesis and differentiation, glycolipid metabolism, prolife
Cell Death Discovery volume 9, Article number: 449 (2023) Cite this article 4849 Accesses 15 Citations 1 Altmetric Metrics details Abstract The initiation, development and resolution of hepatic fibrosis are influenced by various cytokines, chemokines, damage-associated molecular patterns (DAMPs) and ...
Cell Death Differ. 2022;29(11):2303–15. Article CAS PubMed PubMed Central Google Scholar Zhang M, Fu Z, Tian D, Liu E, Dai J, Wang L. Investigation of the interaction between CREB-binding protein and STAT4/STAT6. Mol Biol Rep. 2011;38(7):4805–11. Article CAS PubMed Google ...
Many types of human cells self-destruct to maintain biological homeostasis and defend the body against pathogenic substances. This process, called regulated cell death (RCD), is important for various biological activities, including the clearance of aber
FDA approved Janssen Pharmaceuticals and Legend Biotech’s autologous CAR T-cell therapy Carvykti for the treatment of previously treated, relapsed, or refractory multiple myeloma patients in March 2022. Leucid Bio Leucid Bio is a a spin-out of the UK’s King’s College. Lead by Dr John ...
Cells co-cultured in single cell-specific media or non-optimal mixed media ratios showed increased cell death of either ECs or CCs (Fig. S1E). However, using the optimized mixed media condition, consisting of 50% EC medium and 50% CC medium, we found that 5.5% of cells expressed CD31 ...
Cell Death Dis. 2023;14:68. CAS PubMed PubMed Central Google Scholar Ma L, Zhang L, Zhuang Y, Ding Y, Chen J. Lactobacillus improves the effects of prednisone on autoimmune hepatitis via gut microbiota-mediated follicular helper T cells. Cell Commun Signal. 2022;20:83. CAS PubMed Pub...
while syncytial knots form closer to the term and protrude slightly from the surface of the villi. An increased number of syncytial knots has been reported in the placenta of pregnancies with combined PE and FGR, whether this phenomenon reflects an exaggerated aging or apoptotic death of STB is...