23 June 2011|Open Access Axotomy induces axonogenesis in hippocampal neurons through STAT3 R Ohara ,Y Fujita &T Yamashita Browse broader subjects Diseases Browse Trauma across other nature.com journals Cell Death & Disease(Cell Death Dis) ISSN2041-4889(online)...
Accidental cell death (unregulated necrosis), in contrast to apoptosis, is adenosine triphosphate (ATP)-independent and does not require energy [8]. When cells try to maintain ATP production, they switch to anaerobic glycolysis with the production of lactate, resulting in a pH decrease. The attem...
NK cells are first-line defenders of the immune response against infectious diseases [3] and cancer [4] but they are also important in autoimmune [5,6] and metabolic diseases [7]. They provide rapid responses because they do not require prior priming. They recognize target cells using germlin...
While the impact of health hazards on the most lethal diseases is well documented, how these factors influence necrotic cell death and DAMP production is poorly understood. We first summarize our knowledge of how different life-threatening risk factors influence the necrotic cell death pathways and ...
Here something by Melino and the other co-founder of Cell Death and Depravity,Pierluigi Nicotera, director of the German Centre for Neurodegenerative Diseases (DZNE) in Bonn, and like Kroemer, also Leopoldina member. Eliana Munarriz , Daniele Bano , A. Emre Sayan , Mario Rossi , Gerry Melino...
Cell Death Discovery is a multidisciplinary, international, online-only, open access journal, dedicated to publishing research at the intersection of medicine with biochemistry, pharmacology, immunology, cell biology and cell death, provided it is scientifically sound. The unrestricted access to research ...
International Journal of Molecular Sciences Review Cell Death in Liver Diseases: A Review Layla Shojaie 1,2 , Andrea Iorga 1,2 and Lily Dara 1,2,* 1 Division of Gastrointestinal & Liver Diseases, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles,...
Cell death mechanisms have been associated with the development of inflammatory bowel diseases in humans and mice. Recent studies suggested that a complex crosstalk between autophagy/apoptosis, micro...
7,11, 12, 13, 14 Hence, the virus-modulated expression of miRNAs that can result in the regulation of cell death pathways may explain the pathogenesis and lead to the possible treatment of viral diseases. Viruses can affect cell death pathways by the deregulation of miRNAs, leading to ...
The liver is not oblivious to the passage of time, as ageing is a major risk factor for the development of acute and chronic liver diseases. Ageing produces alterations in all hepatic cells, affecting their phenotype and function and worsening the progno