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Comparison of scMayoMap and other cell annotation tools on 48 real datasets. A Comparison of cell type annotation accuracy in PBMC datasets. Thirteen PBMC scRNA-seq datasets generated by seven sequencing technologies were tested, including two low-throughput plate-based methods (Smart-seq2 and CEL...
Human naive pluripotent stem cells offer a unique window into early embryogenesis studies. Recent studies have reported several strategies to obtain cells in the naive state. However, cell fate transitions and the underlying mechanisms remain poorly unde
demonstrating that Symphony not only maps query cells to the correct broad cluster but also preserves the distance relationships between nearby cells in the same local region (Fig.2d). As a comparison, we calculated k-NN-corr for a simple PC projection of the query cells (with no correction ...
Moving forward, a systematic comparison and benchmarking of E2G perturbation maps generated with multiple CRISPR modifiers and precise edits across multiple tissues should help us define robust principles for E2G interrogation and discovery. Conclusions We present “primary T cell crisprQTL” — a ...
Indoor maps for large shopping centers, airports, and malls Lock or erase a device Compatible with Android 4.1 and later Verdict:Google Find My Device is a reliable phone tracking app. But the app tracks the device only when the Internet connection is on. You can’t track the phone just ...
Based on the coverage filtered VCF-file (see above), we identified homozygous SNPs that distinguish the three strains and removed SNPs that had predominantly coverage in only one of the strains (1st percentile of allele frequency). In most parts of the analysis, we focused on the comparison be...
cultured Movas SMCs, macrophages, B-cells, S100β+mVSc, bone marrow derived mesenchymal stem cells (MSC) and their respective myogenic progeny across five broadband light wavelengths (λ465 - λ670 ± 20 nm). We found that profiles were of sufficient coverage, specificity, and quality to clearl...
Heatmap depicting surface markers with differential expression between the phenotypic classes defined ine. The eight markers with the most significantPvalues from DESeq2 were selected for each comparison between classes. Average expression across all nonlymphoid cells is shown. ITD, internal tandem dupli...
Computational trajectory inference enables the reconstruction of cell state dynamics from single-cell RNA sequencing experiments. However, trajectory inference requires that the direction of a biological process is known, largely limiting its application