(tested using the Shapiro-Wilk test for normality, allp-values < 1 × 10e-4 for each class), therefore a Student’s t-test was applicable. For each of the two classes of interest (astrocytes and immune), we performed independent log-space t-tests for unequal sample sizes and...
9e–h). Fig. 8: CITE-On online cell detection performance on never-before-seen datasets. a–e Best parameter search for frame downsampling: F-1 score (pseudocolor) as a function of score threshold and number of frames for the ABOsup (a), ABOdeep (b), NFtrain (c), NFtest (d),...
The Cellognost indirect haemagglutination (IHA) test was compared with conventional techniques, namely, wet blood film examination, stained thin and thick films, animal inoculation and the microhaematocrit centrifugation, for detecting cases. Sixty-four out of 245 serum samples collected from suspected...
Within this paper, emphasis is given to the model validation and dynamic system behavior. In order to validate the predicted results, data from real fuel cell flight (two 40-minute missions performed during the ENFICA-FC test campaign) have been used and are presented in this paper 展开 ...
Cpf1 is a single-RNA-guided endonuclease of a Class 2 CRISPR-Cas system. Transgenic Res. 2016;25(2):207. Google Scholar Tu MJ, et al. A ‘new lease of life’: FnCpf1 possesses DNA cleavage activity for genome editing in human cells. Nucleic Acids Res. 2017;45(19):11295–304. ...
Host cell proteins (HCPs) are a major class of process-related impurities and require monitoring and documentation of their presence through development and manufacturing. Even in residual amounts, they are known to affect product quality and efficacy as well as patient safety. HCP analysis using ...
ROS1 rearrangements define a unique molecular class of lung cancers. J Clin Oncol 2012;30:863-870. ddIn patients with squamous cell carcinoma, the observed incidence is 2.7% with a confidence that the true incidence of mutations is less than 3.6% in patients with squamous cell carcinoma. ...
(D) Aggregated log2-transformed gene expression in EPN-Neuronal-Precursor-like/GBM-NPC2 cells from each tumor class (rows) for metaprogram genes from either tumor (columns), with genes ordered into those common to EPN and GBM, or specific to either tumor type. (E) Analysis as in (C) ...
including MHC class II molecules (MHCII), which are normally found exclusively in professional antigen-presenting cells44. Unlike AT2 cells, which express high levels of MHCII independent of inflammatory stimuli (Fig.3g)45, ciliated cells demonstrated very low expression of these molecules in homeost...
From scProjection’s estimates of cell population specific abundances, treated as probabilistic class assignments, the class with maximal probability is assigned as the cell population label for each sample. Cell annotation with k-NN label transfer We label RNA mixtures using k-NN based on the labe...