In this review, we briefly reflect on the history of selective covalent targeting, and provide a comprehensive overview of emerging developments from a chemical biology stand-point. Our discussion will reflect o
Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology Article 21 February 2022 The redox language in neurodegenerative diseases: oxidative post-translational modifications by hydrogen peroxide Article Open access 11 January 2021 Change history 17 June 2024 A Correct...
Towards single cell encapsulation for precision biology and medicine 1Introduction Cell encapsulationin biomaterials has a long history in the field of cell therapy; it was initially designed to broaden the availability of donor cell sources by protecting them from immune rejection while providing a sem...
Complete chemical structures of human mitochondrial tRNAs Article Open access 28 August 2020 tRNA dysregulation and disease Article 09 June 2022 Emerging roles of tRNA-derived small RNAs in cancer biology Article Open access 10 July 2023 References Holley, R. W. et al. Structure of a ribo...
biology, it still faces challenges in capturing individual cells’ complete gene expression profiles. Here, we provide a comprehensive overview of scRNA-seq and spatial transcriptomics, including the experimental procedures, computational methods, and data integration strategies. It highlights the impact of...
Medical History. 1980; 24: 129–142. 68. Pearl R. The biology of death. II. Conditions of cellular immortality. The Scientific Monthly. 1921; 12: 321–335. 69. Haff RF, Swim HE. Serial propagation of 3 strains of rabbit fibroblasts; their susceptibility to infections with vaccine virus....
I can only briefly summarize the more recent findings here and provide examples that illustrate some of the major achievements. Furthermore, I discuss a number of questions that still remain open in insect NPH research. However, first I provide a brief history of the detection, identification, ...
currently being developed to intensify drug or therapeutic cell transport across the BBB for their effective accumulation in the brain. Several techniques have been developed for opening the BBB, ranging from the use of chemical and biological substances, osmotic opening, to physical stimuli such as ...
With stem cell therapy and all its regenerative benefits, we are better able to prolong human life than at any time in history.Abbreviations bFGF: Basic fibroblast growth factor BMP: Bone morphogenic proteins DFCs: Dental follicle stem cells DPSC: Dental pulp stem cells EBs: Embryonic ...
CELL CYCLE: HISTORY The adult human body is composed of approximately 200,000 billion (2 × 1014) cells, all of which derive from a single cell, the fertilized egg. In adults, there are subpopulations of cells that continuously divide or retain the capacity to divide to replace cells that ...