Ubiquitin is a 76-amino acid protein, and as such bears many potential sites for additional post-translational modifications. The key features of ubiquitin are its seven Lys residues, all of which can be ubiquitinated, to give rise to isopeptide-linked ubiquitin chains. An eighth chain type, Me...
Rabouw, H. H. et al. Inhibition of the integrated stress response by viral proteins that block p-eIF2–eIF2B association. Nat. Microbiol. 5, 1361–1373 (2020). Article CAS PubMed Google Scholar Cameron, C. M., Barrett, J. W., Mann, M., Lucas, A. & McFadden, G. Myxoma virus...
Power Adjustable 8 Antenna Mobile Signal Jammer 2G / 3G / 4G Lojack Wifi Gps Cell Blocker X8adj Please Contact with us at: Mr.Jerry Brief Description: Vodasafe stationary jammer X8adj can adjust block range is best using in rooms or vehicles. ...
Leverkus, cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms. Mol. Cell 43, 449–463 (2011) Article Google Scholar N. Festjens, T. Vanden Berghe, P. Vandenabeele, Necrosis, a well-orchestrated form of ...
3. Aitken KJ, Block G, Lorenzo A, Herz D, Sabha N, Dessouki O, Fung F, Szybowska M, Craig L, Bagli DJ. Mechanotransduction of extracellular signal-regulated kinases 1 and 2 mitogen-activated protein kinase activity in smooth muscle is dependent on the extracellular matrix and regulated by...
Block M, Gilbert E, Davis C. Metastatic neuroblastoma arising in an ovarian teratoma with long-term survival. Case report and review of the literature. Cancer. 1984;54(3):590–5. Article CAS PubMed Google Scholar Reid HA, van der Walt JD, Fox H. Neuroblastoma arising in a mature cysti...
van den Wildenberg, W.H. Roos, C.M. Gustafsson, G.J.L. Wuite, M. Falkenberg In vitro-reconstituted nucleoids can block mitochondrial DNA replication and transcription Cell Rep., 8 (2014), pp. 66-74 View PDFView articleView in ScopusGoogle Scholar Franceschi, and Campisi, 2014 C. ...
Meeusen S, DeVay R, Block J, Cassidy-Stone A, Wayson S, McCaffery JM, Nunnari J. Mitochondrial inner-membrane fusion and crista maintenance requires the dynamin-related GTPase Mgm1. Cell. 2006;127(2):383–95. Article CAS PubMed Google Scholar Song Z, Ghochani M, McCaffery JM, ...
(2) O-GlcNAcylation can block the Thr405 and Ser406 sites of PKM2, and the stability of PKM2 in tetrameric form is reduced to enhance the aerobic glycolysis, namely Warburg Effect [150]. (3) The binding of histone demethylation enzyme Jumonji-C (JmjC) domain-containing protein 5 (JMJD5)...
(Supplementary information, Fig.S3b). To mitigate potential overfitting of PrismNet, we added dropout39layers after every residual block, and other regularizers including weight decay40and early stopping in the training stage. Importantly, we also applied SmoothGrad41to enable the enhanced saliency ...