H. et al. ALIX and ESCRT-III coordinately control cytokinetic abscission during germline stem cell division in vivo. PLoS Genet. 11, e1004904 (2015). PubMed PubMed Central Google Scholar Iwamori, T. et al. TEX14 interacts with CEP55 to block cell abscission. Mol. Cell. Biol. 30, ...
Abdel-Azim, H., Elshoury, A., Mahadeo, K. M., Parkman, R. & Kapoor, N. Humoral immune reconstitution kinetics after allogeneic hematopoietic stem cell transplantation in children: a maturation block of IgM memory B cells may lead to impaired antibody immune reconstitution. Biol. Blood Marrow...
Cell-block technique when associated with clinical and image data can be used as an ancillary tool for the diagnosis of SBC.doi:10.1016/j.oooo.2025.01.117Gustavo Henrique MartinsDaniel Augusto Barnabé NobreJosé Alcides Almeida de ArrudaFelipe Paiva Fonseca...
Y.; Zhou, L.; Chu, Y.; Zhang, C.; Qin, X.; Yang, P.; Yu, H., SIRT5 Desuccinylates and Activates Pyruvate Kinase M2 to Block Macrophage IL-1beta Production and to Prevent DSS-Induced Colitis in Mice.Cell Rep2017, 19 (11), 2331-2344. ...
Flagellin is the main building block of the organs responsible for moving almost all flagellated bacteria and the primary ligand of receptors like FLS2 (Schuster and Khan1994). Flagellin perception depends on FLS2 heterodimerization with the LRR-RLK co-receptor BRASSINOSTEROID INSENSITIVE 1-ASSOCIATED ...
It is also reported that inhibiting JAK/STAT pathway can block CSC self-renewal [84]. In the breast cancer, expression of a variety of lipid metabolic genes, including carnitine palmitoyltransferase 1B (CPT1B), which encodes the key enzyme for fatty acid b-oxidation (FAO) is also blocked ...
CO2is an important component of pH regulatory mechanisms in biological systems. In an aqueous environment, dissolved CO2partially reacts with water to form H2CO3, which dissociates into HCO3−and H+. The balance between H2CO3and HCO3−levels underlies the most important mechanism of maintaining...
block nonspecific binding, the tissue sections were pre-incubated with 10% normal goat serum for 30 min. Subsequently, they were incubated overnight at 4 °C with primary antibodies in a humidified chamber. The primary antibodies used to validate mast cells included mouse anti-humanCMA1(AbCam, ...
A third study from the Peloton Therapeutics group described an orally active small-molecule inhibitor named PT2385, which is structurally similar to PT2399 (Fig.9B), as a specific antagonist of HIF2α, which can allosterically block PT2385 dimerization with the HIF1α/2α transcriptional partners...
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