The Innovative Medicines Initiative (IMI) launched, on 17 December, a call for proposals for research in three priority areas: antimicrobial resistance, the definition of diseases based on their underlying biology and the creation of a European induced pluripotent stem cell bank. The budget for IMI...
BMC Cell Biology BioMed Central Research article Open Access Identification and characterization of Iporin as a novel interaction partner for rab1 Michael Bayer1, Julia Fischer2, Joachim Kremerskothen2, Edith Ossendorf2, Theodoros Matanis2, Magdalena Konczal2, Thomas Weide3 and Angelika Barnekow*2...
Gene expression is often deduced from the transcriptome based on the central dogma of molecular biology. However, post-transcriptional regulation and translational control of gene expression may alter the initial transcriptional profile1. Therefore, translatome is more accurate than transcriptome as a mea...
Animal research has been indispensable in understanding human biology and disease, and the most commonly used model has been the mouse (Mus musculus). There are now thousands of inbred strains and genetically modified lines available, and some, such as the C57BL/6 strain, have been propagated ...
Stem cell biology iPSC quality control and recognition by morphological differences hESC derivation and media Turning point in stem cell therapy iPSCs Directed differentiation Stem cell obstacles in the future Conclusion Abbreviations References Acknowledgements Author information Ethics declarations Rights and ...
Nature Cell Biology thanks Carsten Janke, Claire Walczak and the other, anonymous, reviewer(s) for their contribution to the peer review of this work. Additional information Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affilia...
Exosomes biology, a rapidly growing field of research, has gained scientists’ attention over the past few decades due to its pivotal role in regulating cellular processes [1]. They transfer biomolecules to target cells and, therefore participate in pathological conditions like cancer [2]. A ...
Home BMC Developmental Biology Article Transgenic and knockout analyses of Masculinizer and doublesex illuminated the unique functions of doublesex in germ cell sexual development of the silkworm, Bombyx mori Research article Open access Published: 21 September 2020 Volume 20, article number 19, (...
2019, Molecular Biology of the Cell Form and function of the vertebrate and invertebrate blood-brain barriers 2021, International Journal of Molecular Sciences View all citing articles on Scopus 2 Present address: University of Cologne, CECAD Imaging Facility, Joseph-Stelzmann-Str. 26, 50931 Cologn...
To make the evaluation more systematic and comprehensive, we additional support biology conservation metrics and batch removal metrics under this task in addition to ARI metric. For biology conservation evaluation, normalized mutual information (NMI) metric is adopted to compare the overlap of two clust...