Review Article16 May 2024 Cell-intrinsic and microenvironmental determinants of metastatic colonization Metastatic colonization involves cancer-cell-intrinsic mechanisms and microenvironmental interactions, and a better understanding of the factors that influence the final, post-extravasation phases is crucial ...
General Biology 1 - Cell Cycle: Meiosis (2) Microtubules, Cell Cycle, and Viruses: Comprehensive Exam Review Cytoskeleton, Cell Signaling and Cell Cycle: A Comprehensive Study Guide Cell Biology Study Questions: Genetic Material, Chromosomes, and Cell Cycle - Prof. Mark A ...
The tumour microenvironment (TME) displays notable heterogeneity, with substantial variability within and between tumours, thereby influencing tumour biology, treatment response, and prognosis [8, 9]. The inherent limitations of conventional therapies, which exclusively target tumour cells while neglecting th...
Explain the ways in which the history of developmental biology can help to understand the current controversies regarding stem cell research Stem cell study in the United States is particularly controversial because of the ethical issues that arise, especially among religious groups in the country. For...
and function. First, we describe the CRISPR–Cas9 application on different T cells. We then discuss its application in the adoptive T cells therapies in preclinical and clinical research. Finally, we review the delivery systems and the high-throughput screening of CRISPR–Cas9 in T cell immunity...
Exosomes biology, a rapidly growing field of research, has gained scientists’ attention over the past few decades due to its pivotal role in regulating cellular processes [1]. They transfer biomolecules to target cells and, therefore participate in pathological conditions like cancer [2]. A ...
Abstract Introduction Metabolomics Technologies and Advancements Metabolomics Applications in Plant Stress Responses, Multi-Omics and Single-Cell Biology Challenges and Future Perspectives Supplementary Materials Author Contributions Funding Institutional Review Board Statement Informed Consent Statement Data Availability...
Meroterpenoids: A comprehensive update insight on structural diversity and biology. Biomolecules 2021, 11, 957. [Google Scholar] [CrossRef] Zbakh, H.; Zubía, E.; Reyes, C.L.; Calderón-Montaño, J.M.; Motilva, V. Anticancer activities of meroterpenoids isolated from the brown alga ...
Osimertinib reduces angiogenesis and PDL1 expression inin ovotumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microe...
To make the evaluation more systematic and comprehensive, we additional support biology conservation metrics and batch removal metrics under this task in addition to ARI metric. For biology conservation evaluation, normalized mutual information (NMI) metric is adopted to compare the overlap of two clust...