which was believed – between the mid-1950s and mid-1970s – to be the organelle within which intracellular proteins are destroyed. Independent lines of experimental evidence gradually eroded the lysosomal hypothesis and resulted in a new idea that the bulk of intracellular proteins are degraded –...
HER2 belongs to the human epidermal growth factor receptor tyrosine kinase family. Its overexpression or hyperactivation is a leading cause for multiple types of cancers. HER2 functions mainly through dimerization with other family members, such as EGFR.
The drugs usually inhibit proteolytic activity; however, reducing expression or synthesis of TMPRSS2 is being considered as a therapeutic target [86]. Camostat mesylate (CM) and nafamostat mesylate (NM) are identified as serine protease inhibitors belonging to the group of small molecule compounds ...
NON-VOLATILE SEMICONDUCTOR MEMORY DEVICE FOR PREVENTING CELL DATA FROM BEING DESTROYED BY LIMITING THE NUMBER OF DATA REWRITE OPERATIONS THROUGH HAVING AN ERASE CONTROL AREA SET FOR HOLDING THE NUMBER OF DATA REWRITE OPERATIONSPURPOSE: A non-volatile semiconductor memory device is provided to limit ...
The server hosting the file being downloaded did not specify the MIME type for that file (e.g., GIF, MID, JAR). Thus, the cellular phone assumes that the file is plain text. Also, the cellular phone might have a limit on the size (in bytes) of text files which is smaller than ...
This study was supported by grants from the German Cancer Aid (Deutsche Krebshilfe 109362), German Research Community (DFG HE 3186/11-1), German-Israeli Foundation for Scientific Research and Development (GIF 1058-7.11/2008), Heidelberger Stiftung Chirurgie and from the Foundation for cancer and ...